DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4822 and Abca7

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001334010.1	Gene:	Abca7 / 27403	MGIID:	1351646	Length:	2167	Species:	Mus musculus

Alignment Length:	336	Identity:	88/336 - (26%)
Similarity:	143/336 - (42%)	Gaps:	64/336 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAG-FGAVCESGEILVNNSPRDMRVFRKMSRYIMQ 139
            |:.:|..|:...:||.:|.:||||||.|::|:| |.....|..||.::...:|...|.......|
Mouse   821 LQGLNLDFYEGHITAFLGHNGAGKTTTLSILSGLFPPSSGSASILGHDVQTNMAAIRPHLGICPQ 885

  Fly   140 TDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNTMAQKLSGGERKRLCI 204
            .:||....||.|.:.....||......:..:.|.:...:|:...:|   |..:.||||.:::|.:
Mouse   886 YNVLFDMLTVEEHVWFYGRLKGVSAAAMGPERERLIRDVGLTLKRD---TQTRHLSGGMQRKLSV 947

  Fly   205 ALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAE 269
            |:..|....|:.:||||.|:|. :|.:.|..|.:....|||:|.|.|        .||...:|.:
Mouse   948 AIAFVGGSRVVIMDEPTAGVDP-ASRRGIWELLLKYREGRTLILSTH--------HLDEAELLGD 1003

  Fly   270 GQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMV---------EAVGNG 325
            ...:..| ||          |||  ..:|......:.|     .|:..:|         :|.|:.
Mouse  1004 RVAMVAG-GS----------LCC--CGSPLFLRRHLGC-----GYYLTLVKSSQSLVTHDAKGDS 1050

  Fly   326 KVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISP----------KLLE--------AKC 372
            :..|....: :|...|:.|..|.|.|     |:.::..:|          ::||        |:.
Mouse  1051 EDPRREKKS-DGNGRTSDTAFTRGTS-----DKSNQAPAPGAVPITPSTARILELVQQHVPGAQL 1109

  Fly   373 SWWLQYKLLLV 383
            ...|.::||||
Mouse  1110 VEDLPHELLLV 1120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	59/200 (30%)
		3a01204	67..654	CDD:273361	88/336 (26%)
		ABC2_membrane	381..587	CDD:279410	3/3 (100%)
Abca7	NP_001334010.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1042..1088		11/51 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1172..1192
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2126..2167
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000