Protein Alignment CG4822 and Abcg4

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 631
• Identity: 251/631 - (39%)
• Similarity: 361/631 - (57%)
• Gaps: 63/631 - (9%)

  Fly    45 YLPSWPAVNLQFSELCYVVPDQTNASKT--KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA 107
            :||...||:::|.||.|.|.:.....|.  ||:|:.::|.|...||..|:|||||||:|.:|:||
Mouse    52 HLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILA 116

  Fly   108 GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLE 172
            |:......|:||||..||::|.|||||.||||.|:|....||||.|:::|||||.::..:|:  |
Mouse   117 GYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKK--E 179

  Fly   173 VIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLK 237
            ::.|||..|.|....:|....||||:||||.|||||||||||:|.||||:|||..|..|.::|:|
Mouse   180 LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 244

  Fly   238 VLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFI 302
            .||.|||||||:||.||||:|||.|.:|:|::|||:::|..:|::|:||..||.||..:||||||
Mouse   245 SLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFI 309

  Fly   303 IEVACLEYGGSYHEPMV-EAVGNGKVA----RWSP-----PA-----------VEGETTTTKTDT 346
            ||||..|||..  .||: .||.||...    :.||     ||           :|..|..|.|.|
Mouse   310 IEVASGEYGDL--NPMLFRAVQNGLCTMAEKKSSPGKNELPAHCPTCPPELDPIESHTFATSTLT 372

  Fly   347 TSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVG 411
                                          |:.:|..|..:.:.||.....|:|..::::.:|:|
Mouse   373 ------------------------------QFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIG 407

  Fly   412 SLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMV 476
            .||..:|..|||...|.||:|..::..::..:||.:|.||.|:.:..||:.|.||.|.:||.|..
Mouse   408 LLYLHIGDDASKVFNNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKT 472

  Fly   477 TSKLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLI-SSRLSLVNAMFM 540
            .:.:|...:..|:|.||||.|:.||.|..||.:...:|..|||.:.|.|||| ::..||..|.|:
Mouse   473 MADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFV 537

  Fly   541 GPVLAVPLILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFC 605
            |||.|:|::|.|.:.:.:   ..|...:::..:|||:|:..|||:.::|...|....|.|.:  |
Mouse   538 GPVTAIPVLLFSGFFVSF---KTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLDEQ--C 597

  Fly   606 SFKKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRLK 651
            .|:..:::|..|..|..........|..|:|...:.||.::|.|:|
Mouse   598 PFRDPQIILRELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYRVK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	242/609 (40%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	251/631 (40%)