Protein Alignment CG4822 and wht-6

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_498425.2
• Gene: wht-6 / 188911
• WormBaseID: WBGene00007060
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 625
• Identity: 164/625 - (26%)
• Similarity: 288/625 - (46%)
• Gaps: 72/625 - (11%)

  Fly    51 AVNLQFSELCYVVP--------DQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA 107
            ||:..:|.|..:||        ..|...:.:.:|:.|:|...|.||.|::|.||||||||||:|
 Worm    18 AVSPGYSTLGDIVPVSLHWNNITVTTIKEKRLLLKNVSGYAKSGELLALMGASGAGKTTLLNML- 81

  Fly   108 GFGAVCES-------GEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKEL 165
                :|.:       |.|.||.:....:: ..:|.:..|.::.....||.|.:::.|.|::....
 Worm    82 ----MCRNLKGLSTEGTITVNGNEMAHKI-SSISGFAQQEELFVGTLTVKEYLMIQAKLRINGSK 141

  Fly   166 NLKQKLEVIDEILGMLRL---KDT-LNTMAQK--LSGGERKRLCIALELVNNPPVIFLDEPTTGL 224
            .|::  :.:.::|..|:|   :|: :..:.:|  :||||.:||..|.|:::||.::|.|||||||
 Worm   142 KLRE--DRVTDVLHQLKLWKCRDSKIGVIGEKKGISGGEARRLTFACEMLSNPSLLFADEPTTGL 204

  Fly   225 DDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFG 289
            |...:...|.:||.:|..|||:||:||.||:::::|...|..||.|...:||.....:.|.:..|
 Worm   205 DSFMAESVIQILKGIAKTGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQESISFFEKCG 269

  Fly   290 LCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFY 354
            ...|..|||:::||....:       :|..|...|.::.:......:.:......:..|..|
 Worm   270 HRVPDEYNPSEWIIYKLAV-------QPGQEKQSNDRIQKIVEQYEDSDHQKRVMEQLSDVS--- 324

  Fly   355 ERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGT 419
                  |:|.|..:. :.:.:.|...|..|..|.:||.......|....|:..|.:|.||.....
 Worm   325 ------EKIPPPEMH-RANVFTQIFALSTRCGIDVWRAPQLTLAKVIQKILFGLFIGLLYLRTPY 382

  Fly   420 SASKALFNF-GFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSM 483
            .| :.:.|. |.:|.:...|:|.....::.:...|..|:.|||::..|.|.:||.|...|.:|..
 Worm   383 DA-RGIHNINGALFFLAGEYIYSTAYAIMFFLNNEFPLVAREYHDGLYNLWTYYFARCISLIPLF 446

  Fly   484 FILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISS--RLSLVNAMFMGPVLAV 546
            ....:|.|.|||.:........:..:...|..:.:..:.:||:.:|.  ..:.:.|:...|
 Worm   447 STDGLILLFIVYWLIGLNTSVMQVIVASIITVLASQAASAFGIAMSCIFPTAQMTAVMASP---- 507

  Fly   547 PLILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLY----DY------GRADTICEDT 601
            ||:|..::|..||........:|:|..:|..|.:.||||.:.:    |:      ...::...|.
 Worm   508 PLVLFRLFGGLYGNTNTFPAAIRWLQWISMYRFAFEGLVVNQWSEIDDFHSNAKNNWTNSTTNDV 572

  Fly   602 EIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVA 641
            ..:.:|.:|.:.|..:|.        :...::|||:..:|
 Worm   573 LDYFAFSESAIPLDIIGL--------ILISLAFYLIGFIA 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	158/601 (26%)
wht-6	NP_498425.2	YlqF_related_GTPase	<3..>81	CDD:483945	25/62 (40%)
		3a01204	50..613	CDD:273361	157/593 (26%)