Protein Alignment CG4822 and wht-2

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 185/663 - (27%)
• Similarity: 300/663 - (45%)
• Gaps: 78/663 - (11%)

  Fly     1 METASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPD 65
            :....|..|:..|.||:|:....:..                     :|..:::
 Worm     9 LSVGQSEYGAAASMISALEAVDPVTL---------------------TWHNISI----------- 41

  Fly    66 QTNASKT-KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLL--AGFGAVCESGEILVNNSPRDM 127
              :|.|: |.||..|:|:....:|.|::|.||||||||||:|  .....:..||.:.||.....
 Worm    42 --HAEKSGKQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLSRNLRGLETSGSVKVNGHELG- 103

  Fly   128 RVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKL-GKELNLKQKLEVIDEILGMLRLKDT-LNTM 190
            |....:|.|..|.::.....||.|.:.:.|.|:: |.....::::..:...||:.:.::| :.|:
 Worm   104 RGITAISGYAQQDELFVGTLTVKEYLDIQAKLRVNGDSEKRRRRVGNVMSQLGLYKCQNTRIGTI 168

  Fly   191 -AQK-LSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTP 253
             .|| :||||.:||..|.||::||.::|.||||||||...:...:.:|..||..||||||:||.|
 Worm   169 GGQKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSFMAESVVQVLSNLAKSGRTVICTIHQP 233

  Fly   254 SAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPM 318
            |::::.|.|.|..:|.|:..:.|...:.:.|.::.|..||..:||||.||....:       .|.
 Worm   234 SSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFACPRNFNPADLIIHTLAV-------MPN 291

  Fly   319 VEAVGNGKVARWSPPAVEGETTTTKTDTTS-GASSFYERDQFDEEISPKLLEAKCSWWLQYKLLL 382
            .|.....::          |...||...:| |.:..:..::.||...|. ...|.....|...||
 Worm   292 EEDKCRQRI----------EVIYTKFQNSSYGRTLKFGVEKSDEGQRPS-ERHKTGILTQIGALL 345

  Fly   383 VRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNF-GFMFTIVIAYLYLPMMPV 446
            .|..|..||:.|..:.|.....::.|.:|.||. .....|..:.|. |.:|.:|....|..:..:
 Worm   346 ERSAIDTWRNPSLTRAKVIQKSIMGLFIGLLYL-QSPLTSIGISNLNGALFYLVCELTYSTIFGI 409

  Fly   447 LLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLM--SSQPLEWFRFAM 509
            |.:.|.:..|:.|||::..|.:.|||.|...|.||......:|.|.:.|.|  .|..:....:|.
 Worm   410 LNFLPADFPLVSREYHDGLYSVFSYYVARCLSYLPLFTADGLIMLLVSYWMVGFSSSITQVLYAC 474

  Fly   510 LFTIAFVTALTSDSFGLLISS-RLSLVNAM-FMGPVLAVPLILLSIYGIGYGGGTYISPLMRFLM 572
            |  |||:...:|.:.|::||. ..||..|| ..||:|.    |||:.|..|.....:...:.::.
 Worm   475 L--IAFLIEQSSSACGIMISCISPSLPIAMSTAGPMLT----LLSLTGGLYANVGALPSYISWIQ 533

  Fly   573 HLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFYLL 637
            :||:.|:..|....:.:    :....::|.|:...|:..| |:.|.|....:...|..:.:|.|:
 Worm   534 YLSWFRYGFEAFAINQW----SSVNEQNTTIWTDEKRDSV-LSQLSFRAEMFYPDLFIMSAFILI 593

  Fly   638 FTVAAYFMIRLRL 650
            |....|..:.||:
 Worm   594 FYTIGYAGLALRV 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	178/597 (30%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	177/594 (30%)