Protein Alignment CG4822 and wht-7

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001391160.1
• Gene: wht-7 / 175864
• WormBaseID: WBGene00021535
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 705
• Identity: 180/705 - (25%)
• Similarity: 327/705 - (46%)
• Gaps: 94/705 - (13%)

  Fly     1 METASSVKGSTTSQISSLQYSSDIN------ADSLEP------------DQSEDFQTVLGLKYLP 47
            |..::.::||..| :|.:..:|||:      .:.|.|            |.|||:.:..||
 Worm     1 MLKSNVIQGSIES-MSVVDSTSDIDKADKSFMEELRPKMLLTWHDISVSDSSEDYSSNSGL---- 60

  Fly    48 SWPAVNLQFSELCYV-VPDQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA--GF 109
                    |.:.|.: |.|....|..|.||..|.|:....|:||||||||||||||||:|.  ..
 Worm    61 --------FGKCCPIKVGDVEKMSVEKRILDSVFGVARPGEVTAIIGPSGAGKTTLLNVLTKRNL 117

  Fly   110 GAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNL---KQKL 171
            ..:..:|.:.||....:....|::..|:.|.|......||.|.:...|.||:|.|.:|   ::::
 Worm   118 SNLKATGSVKVNGIRAERSYMRQVCAYVQQDDCFIGSLTVEEHLKFMAKLKMGSEYDLNEQERRV 182

  Fly   172 EVIDEILGMLRLKDT-LNTMAQK-LSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIA 234
            :.:...||:.::.|: :.|..:| :||||:|||..|.|::.:||::..||||:|||...:.|.:.
 Worm   183 KSVMRSLGLEKIADSIIGTRTRKGISGGEKKRLAFASEILTSPPILICDEPTSGLDSFLAYQVVC 247

  Fly   235 LLKVLA-AGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNP 298
            :||.|| ....|::.:||.||:::|::.|::|::..|...:.|..|..........|..|:.:||
 Worm   248 VLKKLAETRNMTILLTIHQPSSQVFQLFDSIYMMVNGDVAFCGSQSGAEKMWSEMKLPIPMNFNP 312

  Fly   299 ADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYER-----DQ 358
            :|..:...      |..:...|.:...::         |:..||...:..|.|.|.|.     |:
 Worm   313 SDHYLATM------SIRDQAEETLKKNQI---------GKICTTFKYSELGKSVFKESSGREVDE 362

  Fly   359 FDEEIS-------------PKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLV 410
            .|...|             |:.   ..|::.|.:.|..|....:.|:.:.:|::.:.:|::|:|.
 Worm   363 RDRAFSEDWRRRYATTFGRPRF---GASFFQQIRALTWRASKTVLREPTLLKVQTFQSIIIAILT 424

  Fly   411 GSLYFGMGTSASKALFNF-GFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAA 474
            |.:|........:.:.|. |.::.::....::....|:.:|..|:|...||.:::.||:|:|:.:
 Worm   425 GLVYTNNSPVDQQKIMNINGSLYQMISNMAFMFQFSVVHHFCLEMNTFYRETSSRLYRVSAYFIS 489

  Fly   475 MVTSKLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVN-AM 538
            ...::|||..:.|||:.||:|.||........|.:...:..:....:.|.|.:.|.....|| |:
 Worm   490 KNLAELPSYIVSAVIFTSILYWMSGLVPIIDSFLIYMLVGILVQNIAISIGYMFSCIFGTVNLAV 554

  Fly   539 FMGPVLAVPLILLSIYGIGYGGGTYIS--PLMRF---LMHLSYLRHSMEGLVASLYDYGRADTI- 597
            .:.|:..||::..        ||.:|:  .|..:   :.:|||..:..|.:..:.:.:.....:
 Worm   555 AVMPIFVVPMMAF--------GGFFINQDTLQWYFVPMKYLSYFGYGYEAVAIAQWTHVEEIPVS 611

  Fly   598 -CEDTEIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRLK 651
             |..:...||...:.||.: :.|:..::...:|.:.....:|...|:..:.:|:|
 Worm   612 GCSSSLAHCSRNGTDVLNS-MSFKPSNFWVDISVMAFMIFVFRFLAFMALYVRVK 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	160/620 (26%)
wht-7	NP_001391160.1	3a01204	40..666	CDD:273361	170/665 (26%)