Protein Alignment CG4822 and wht-1

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001348731.1
• Gene: wht-1 / 175859
• WormBaseID: WBGene00015479
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 190/706 - (26%)
• Similarity: 313/706 - (44%)
• Gaps: 121/706 - (17%)

  Fly    13 SQISSLQYSSDINADSLE--PDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPD--QTN----- 68
            |..|::..:..:|.|.||  ..|....|.|     :|.  ..||.:|.|....|:  .||
 Worm    13 SLFSNMMLAEMMNDDQLELLKHQQTGIQPV-----VPE--GCNLYWSSLNVTGPETKPTNFVDRF 70

  Fly    69 -----ASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA--GFGAVCESGEILVNNSPRD 126
                 ..:.|.||..|:||..|.:|.||:|.||||||||:|:|.  ....:...|.||::....:
 Worm    71 RNNMPKRRVKEILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRAN 135

  Fly   127 MRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLG--------KELNLKQKLEVIDEILGMLRL 183
            ....|:||.::.|.|:.....|..|.:...|.|::|        ::|.::|.|..    :|:.:.
 Worm   136 KWKIREMSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQ----MGLKKC 196

  Fly   184 KDTLNTMAQKLSG---GERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRT 245
            .||:..:..:|.|   ||:|||..|.|::..|.::|.||||:|||...:...:..|:.||..|.|
 Worm   197 ADTVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGMT 261

  Fly   246 VICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACL-- 308
            ||.:||.||:.::.:.:.|.::|.|:.:|.|.|...||..:..|..||..|||||.:|....:
 Worm   262 VIITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFEKCGYPCPAYYNPADHLIRTLAVID 326

  Fly   309 --------------------EYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSF 353
                                :.|.|     |.|:||....| :...|.|..|:.||.|      |
 Worm   327 SDRATSMKTISKIRQGFLSTDLGQS-----VLAIGNANKLR-AASFVTGSDTSEKTKT------F 379

  Fly   354 YERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMG 418
            :.:|.            ..|:|.|:..|..|..:.:.||.:.:.::....::.|.:.|.::|...
 Worm   380 FNQDY------------NASFWTQFLALFWRSWLTVIRDPNLLSVRLLQILITAFITGIVFFQTP 432

  Fly   419 TSASKALFNFGFMFTIVIAYLYLPMMPVLLYFP------TEINLLKREYNNQWYRLSSYYAAMVT 477
            .:.:..:...|.||.      ::..|..:|.||      .|:.::.||..|..||.|:|:.|...
 Worm   433 VTPATIISINGIMFN------HIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSAYFLAKNI 491

  Fly   478 SKLPSMFILAVIYLSIVYLMSS-QPLEW-FRFAMLFTIAFVTALTSDSFGL-LISSRLSLVNAMF 539
            ::||...||.::|.:|||.||. .|..| :.||.|.||.......|.|:.: .|.:...:  ||.
 Worm   492 AELPQYIILPILYNTIVYWMSGLYPNFWNYCFASLVTILITNVAISISYAVATIFANTDV--AMT 554

  Fly   540 MGPVLAVPLILLSIYGIGYGGGTYIS-----PLMRFLMHLSYLRHSMEGLVASLYDYGRADTICE 599
            :.|:..||::..        ||.:|:     ...::|..|||.::..|.|..:.:|..:....|.
 Worm   555 ILPIFVVPIMAF--------GGFFITFDAIPSYFKWLSSLSYFKYGYEALAINEWDSIKVIPECF 611

  Fly   600 DTEIFCSF------KKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLR 649
            ::.: .:|      |....:|..:.|...|.::.:|.|...::...:.||..:.:|
 Worm   612 NSSM-TAFALDSCPKNGHQVLESIDFSASHKIFDISILFGMFIGIRIIAYVALLIR 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	175/648 (27%)
wht-1	NP_001348731.1	3a01204	76..667	CDD:273361	173/636 (27%)