Protein Alignment CG4822 and abch-1

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_495320.1
• Gene: abch-1 / 174078
• WormBaseID: WBGene00016973
• Length: 595
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 137/624 - (21%)
• Similarity: 248/624 - (39%)
• Gaps: 106/624 - (16%)

  Fly    75 ILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEI-LVNNSPRDMRVFRKMSRYIM 138
            ||:.::....|.|:.||:|.:.:||||||..|.. ||..:.|.| :::......|.|.|...:|.
 Worm    36 ILKNISFTATSGEIHAIVGVADSGKTTLLEALTS-GAGGDIGGIAMLDKFMLTRRRFNKFCSHIN 99

  Fly   139 QTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEV---IDEILGMLRLKDTLNTMAQKLSGGERK 200
            ..:...|..:|..::...|.|.|.   :....||:   |.|:..|..:....:...:.||...|:
 Worm   100 YRNQYPSSLSVRSLLYYHARLCLS---STHTSLEIDHRISELSAMFDVIGYAHDKLEDLSFSARR 161

  Fly   201 RLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAG-GRTVICSIHTPSAKIFEMLDAV 264
            |:...:||:.:|.:..:|:||..|..||:.|.|..|...||. .|.:|.::....:.:..:|.:.
 Worm   162 RVMTVMELLKDPILTIIDDPTAYLSPLSAYQLIYALHFYAAKFNRIIIITLRNVRSDLSHLLGSA 226

  Fly   265 YVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVAR 329
            ..|..|:..|.|:...:....|..|..||...|||.:.:.:..::     .|.|      .||..
 Worm   227 TCLFYGEVAYSGQMRLLPNHFKKAGFECPPNENPAAYYLSLLTID-----KESM------QKVME 280

  Fly   330 WSPPAVEGETTTTKTDTTS--------GASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRML 386
            ....|.:.....|..||:|        |.....:..:.:..||....       :.::.:|  .|
 Worm   281 TQEKATKLVAFRTDNDTSSDISGSSATGTGVLLDSGRKNPSISTVAA-------ILFRRVL--SL 336

  Fly   387 IQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFP 451
            |......|...|     |...:....|.|...||...:||     |..::.:||| ::..::.||
 Worm   337 IGSTPSNSLAGL-----IAFPVTAAVLSFLRPTSLPSSLF-----FWKLLTFLYL-LLQTIVIFP 390

  Fly   452 --TEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFIL------AVIYLSIVYLMSSQPLEW-FRF 507
              ::.:||.       :|..:.|....:..:.|:|.|      :.:::.||.        | |:.
 Worm   391 NYSKTSLLS-------FRECNLYCQTTSLTIFSIFFLVYSCIQSSLFVGIVL--------WSFKS 440

  Fly   508 AMLFTIAF-VTALTSDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGIGYG-GGTYISPLMRF 570
            ..:|.|:. :..|:..||.:.......|.|...:  |:...:|:|:.:..|.| .||..|..:::
 Worm   441 EAMFQISLNLFLLSIFSFSIFTICARYLKNCSNI--VILQTIIILAFFVSGNGVTGTTTSSSIQY 503

  Fly   571 LMHL----SYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHYLW----- 626
            .:.:    :|....:..|::|..|...           |:|......|:.....:::..|
 Worm   504 YIGVINPFNYSNFLLSKLLSSSIDNEE-----------CTFPSYMCKLSMNLHSDLYPPWYAPND 557

  Fly   627 ---SLSCLMSFYLLFTVAAYFM------IRLRLKHSEVS 656
               :.:.|....|.|.|.::|:      ::|: ||.:.|
 Worm   558 VFTNFAILFCLSLTFLVISFFIHLTEPSVQLK-KHMKQS 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	136/620 (22%)
abch-1	NP_495320.1	P-loop containing Nucleoside Triphosphate Hydrolases	18..238	CDD:476819	56/205 (27%)