Protein Alignment CG4822 and wht-4

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_494495.3
• Gene: wht-4 / 173671
• WormBaseID: WBGene00017179
• Length: 636
• Species: Caenorhabditis elegans
• Alignment Length: 704
• Identity: 183/704 - (25%)
• Similarity: 315/704 - (44%)
• Gaps: 124/704 - (17%)

  Fly     3 TASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPDQT 67
            |.:|::.:|:.       |:.|..|:  .|.||.     |.|.: :|       |.|...|| |.
 Worm     5 TTASMRDATSK-------STMITVDT--GDGSEK-----GRKTI-AW-------SGLVATVP-QA 46

  Fly    68 NASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGF--GAVCESGEILVNNSPRDMRVF 130
            ...: |.::|.|:|:....|:.|::|.||||||||:|:||..  ..|...|::.||......:..
 Worm    47 GGGR-KEVIRNVSGVAEPGEVLALMGGSGAGKTTLMNILAHLDTNGVEYLGDVTVNGKKITKQKM 110

  Fly   131 RKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNTM----- 190
            |:|..|:.|.|:.....||.|.:...|:::: |...::||:|.::.:|..:.|.|..||:
 Worm   111 RQMCAYVQQVDLFCGTLTVREQLTYTAHMRM-KNATVQQKMERVENVLRDMNLTDCQNTLIGIPN 174

  Fly   191 -AQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPS 254
             .:.:|.||:|||..|.|::.:|.::|.||||:|||...:|:.:..|..||..|:|:|..:|.||
 Worm   175 RMKGISIGEKKRLAFACEILTDPKILFCDEPTSGLDAFMASEVVRALLDLANKGKTIIVVLHQPS 239

  Fly   255 AKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFG--LCCPITYNPADFII------------EV 305
            :.:|.|...|..:|.|:.||.|....:.||....|  ...|.:||||||::            :|
 Worm   240 STVFRMFHKVCFMATGKTVYHGAVDRLCPFFDKLGPDFRVPESYNPADFVMSEISISPETEQEDV 304

  Fly   306 ACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLEA 370
            ..:||  ..||.....:|...:.:          |.|..|...|    |..|:.|.|     ...
 Worm   305 TRIEY--LIHEYQNSDIGTQMLKK----------TRTAVDEFGG----YGDDEDDGE-----SRY 348

  Fly   371 KCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIV 435
            ..::..|:::||.|.|...:||...::::|...:..|:|||.:.:.:...........|.|:...
 Worm   349 NSTFGTQFEILLKRSLRTTFRDPLLLRVRFAQILATAILVGIVNWRVELKGPTIQNLEGVMYNCA 413

  Fly   436 IAYLYLPMMPVLLYFP------TEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIV 494
                  ..|..|.|||      :|:.:..||:.:..|.:.:|:.|...::||...||.:||.:|:
 Worm   414 ------RDMTFLFYFPSVNVITSELPVFLREHKSNIYSVEAYFLAKSLAELPQYTILPMIYGTII 472

  Fly   495 YLMSSQ---------------PLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVNAMFMGPVL 544
            |.|:..               .|.|    :..:||:|.|......||:::         || |:.
 Worm   473 YWMAGLVASVTSFLVFVFVCITLTW----VAVSIAYVGACIFGDEGLVVT---------FM-PMF 523

  Fly   545 AVPLILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTI--CE-------D 600
            .:|::   ::|..|.....|....:::..:|:.:|..|.|.|:  .:...|.|  |:       .
 Worm   524 VLPML---VFGGFYVNANSIPVYYQYVSFVSWFKHGFEALEAN--QWKEIDKISGCDLINPLNAT 583

  Fly   601 TEIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRLKHSE 654
            |..:|.......:|...|.:...|...|...|||: ::.:.....:::|::.::
 Worm   584 TTGYCPASDGPGILTRRGIDTPLYANVLILFMSFF-VYRIIGLVALKIRVRFAK 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	166/638 (26%)
wht-4	NP_494495.3	3a01204	49..636	CDD:273361	166/635 (26%)