Protein Alignment CG4822 and w

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_061509581.1
• Gene: w / 1271671
• VectorBaseID: AGAMI1_013186
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 742
• Identity: 181/742 - (24%)
• Similarity: 319/742 - (42%)
• Gaps: 135/742 - (18%)

  Fly    10 STTSQISSLQYSSDINADSLEPDQSEDFQTVL-------------------GLKYLPSWPAVNLQ 55
            |::.:.||..|......|:|....:.|..|::                   .|.|  :|..:::
Mosquito    19 SSSRRYSSSSYQDQSMDDALNTTLTNDKATLIQVWKPKSYGSVKGQIPQCERLTY--TWKEIDV- 80

  Fly    56 FSE----------LC-----YVVPDQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNL 105
            |.|          ||     .....:.:.:..|.:|:.|.|:..|.||.|::|.||||||||||.
Mosquito    81 FGEAPTDGKPREPLCTRLRNCCTRQRKDFNPRKHLLKNVTGVAKSGELLAVMGSSGAGKTTLLNA 145

  Fly   106 LAGFGA-----VCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKEL 165
            || |.:     :..:....:|..|.:....|....|:.|.|:.....|..|.::..|.|::|:::
Mosquito   146 LA-FRSPPGVKISPNAVRALNGVPVNAEQLRARCAYVQQDDLFIPSLTTREHLLFQAMLRMGRDV 209

  Fly   166 NLKQKLEVIDEILGMLRLKDTLNTM------AQKLSGGERKRLCIALELVNNPPVIFLDEPTTGL 224
            ....|...:.|:|..|.|....:|:      .:.|||||||||..|.|.:.:|.::..||||:||
Mosquito   210 PASVKQHRVQEVLQELSLVKCADTIIGAPGRIKGLSGGERKRLAFASETLTDPHLLLCDEPTSGL 274

  Fly   225 DDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFG 289
            |...:...:.:||.:|..|:|:|.:||.||::::.:.|.:.::|||:..:.|.......|....|
Mosquito   275 DSFMAHSVLQVLKGMAMKGKTIILTIHQPSSELYCLFDKILLVAEGRVAFLGSPYQSAEFFSQLG 339

  Fly   290 LCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVAR------WSPPAVEGETTTTKTDTTS 348
            :.||..||||||.:::..:       .|..||.....:.:      .||.|.|    ..:|.:.:
Mosquito   340 IPCPPNYNPADFYVQMLAI-------APAKEAECRDMIKKICDSFAVSPIARE----VLETASVA 393

  Fly   349 GASSFYERDQFDEEISPKLLEA---------KCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNI 404
            |..       .||   |.:|:.         :.|||.|:..:|.|..:.:.:|...:|::.....
Mosquito   394 GKG-------MDE---PYMLQQVEGVGSTGYRSSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTA 448

  Fly   405 V--------------------------LALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPM 443
            |                          :|.|:||:|||........:...|.:|..:....:..:
Mosquito   449 VGSRGPSSDLPELTTCFPCFFSPRPQMVATLIGSIYFGQVLDQDGVMNINGSLFLFLTNMTFQNV 513

  Fly   444 MPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLMSSQPLEWFR-- 506
            ..|:..|..|:.:..||..::.||:.:|:.....::||....:..::.||.|     |:...|
Mosquito   514 FAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVFTSITY-----PMIGLRTG 573

  Fly   507 ----FAMLFTIAFVTALTSDSFGLLISSRLSLVN-AMFMGPVLAVPLILLSIYGIGYGGGTYISP 566
                ...||.:..| |..|.|||.|||...|.:: |:.:||.:.:|.:   |:|..:.....:..
Mosquito   574 ATHYLTTLFIVTLV-ANVSTSFGYLISCASSSISMALSVGPPVVIPFL---IFGGFFLNSASVPA 634

  Fly   567 LMRFLMHLSYLRHSMEGLV----ASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHYLWS 627
            ..::|.:||:.|::.|.|:    :::.|   .:..|....:.|. :..:::|....|....:...
Mosquito   635 YFKYLSYLSWFRYANEALLINQWSTVVD---GEIACTRANVTCP-RSGEIILETFNFRVEDFALD 695

  Fly   628 LSCLMSFYLLFTVAAYFMIRLRLKHSE 654
            ::||.:..:||.:.|...:.||.:..|
Mosquito   696 IACLFALIVLFRLGALLCLWLRSRSKE 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	165/649 (25%)
w	XP_061509581.1	None