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Protein Alignment CG4822 and Abcg5

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_446206.2	Gene:	Abcg5 / 114628	RGDID:	620298	Length:	652	Species:	Rattus norvegicus

Alignment Length:	682	Identity:	169/682 - (24%)
Similarity:	271/682 - (39%)	Gaps:	152/682 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TVLGLKYLPSWPAVNLQFSELCYVVP----DQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGK 99
            :|.|.:...|...:|:.||....|.|    ........:.||:.|:....|.:...|:|.||:||
  Rat    29 SVTGSEARHSLGVLNVSFSVSNRVGPWWNIKSCQQKWDRKILKDVSLYIESGQTMCILGSSGSGK 93

  Fly   100 TTLLNLLAG----FGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLK 160
            ||||:.::|    .|.:  .||:.||........|:....|::|:||..|..||.|.:...|.|.
  Rat    94 TTLLDAISGRLRRTGTL--EGEVFVNGCELRRDQFQDCVSYLLQSDVFLSSLTVRETLRYTAMLA 156

  Fly   161 LGK---------------ELNLKQKLEVIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVN 210
            |..               ||:|.   .|.|:::|        |.....:|.|||:|:.||.:|:.
  Rat   157 LRSSSADFYDKKVEAVLTELSLS---HVADQMIG--------NYNFGGISSGERRRVSIAAQLLQ 210

  Fly   211 NPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQ 275
            :|.|:.|||||||||.::::..:.||..||...|.||.:||.|.:::|...|.:.:|..|:.|:.
  Rat   211 DPKVMMLDEPTTGLDCMTANHIVLLLVELARRNRIVIVTIHQPRSELFHHFDKIAILTYGELVFC 275

  Fly   276 GKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETT 340
            |....::.|..|.|..||...||.||.:::
  Rat   276 GTPEEMLGFFNNCGYPCPEHSNPFDFYMDL----------------------------------- 305

  Fly   341 TTKTDTTSGASSF--YERDQFDE------EISPKLLE-------AKCSWWLQYK----------- 379
             |..||.|.....  |:|.|..|      :|..|:||       .|....:.:|
  Rat   306 -TSVDTQSREREIETYKRVQMLESAFRQSDICHKILENIERTRHLKTLPMVPFKTKNPPGMFCKL 369

  Fly   380 -LLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALF--NFGFMFTIVIAYLYL 441
             :||.|:...:.|:|..:.::...|:::.|.:......:..:..|...  ..|.::.:|.|..|.
  Rat   370 GVLLRRVTRNLMRNKQVVIMRLVQNLIMGLFLIFYLLRVQNNMLKGAVQDRVGLLYQLVGATPYT 434

  Fly   442 PMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLMSSQPLEWFR 506
            .|:..:..||....:..:|..:..|:......|.|...||...:..||:.|:.|.......|..|
  Rat   435 GMLNAVNLFPMLRAVSDQESQDGLYQKWQMLLAYVLHALPFSIVATVIFSSVCYWTLGLYPEVAR 499

  Fly   507 FAMLFTIAFVTALTSDSFGLLISSRLSLV-NAMFMGPVLAVPLI-LLSIYGIGYGGGTYISPL-- 567
            |..     |..||.:..   ||...|:|| ..|...|.:...:: ||||.|:..|.| :|..:
  Rat   500 FGY-----FSAALLAPH---LIGEFLTLVLLGMVQNPNIVNSIVALLSISGLLIGSG-FIRNIEE 555

  Fly   568 ----MRFLMHLSYLRHSMEGLVASLYDYGRADT------------ICEDTE-------------- 602
                ::.|.:.::.::..|.||.:.: ||...|            :|..|:
  Rat   556 MPIPLKILGYFTFQKYCCEILVVNEF-YGLNFTCGGSNTSVPNNPMCSMTQGIQFIEKTCPGATS 619

  Fly   603 -------IFCSFKKSKVLLAFLGFENMHYLWS 627
                   |..||..:.|:|..:.|:...||.|
  Rat   620 RFTTNFLILYSFIPTLVILGMVVFKVRDYLIS 651

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.