Protein Alignment CG4822 and Abcg1

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 680
• Identity: 262/680 - (38%)
• Similarity: 383/680 - (56%)
• Gaps: 68/680 - (10%)

  Fly     1 METASSVKGSTTSQISSLQYSSDINADSLEPD--------QSEDFQTVLGLKYLPSWPAVNLQFS 57
            |....||..|....:||       |.|.:|.|        ...:|........||...|||::|.
Mouse    23 MTEPKSVCVSVDEVVSS-------NVDEVETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFK 80

  Fly    58 ELCYVVPDQTNASKT--KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEILV 120
            :|.|.||:.....|.  ||:|:.::|.|:|.||.||:|||||||:||:|:|||:......|.:|:
Mouse    81 DLSYSVPEGPWWKKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLI 145

  Fly   121 NNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKD 185
            |..|||:|.|||:|.||||.|:|....||.|.|:::|:|||.::  .:.:.|::.|||..|.|..
Mouse   146 NGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLP 208

  Fly   186 TLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSI 250
            ..||....||||:||||.|||||||||||:|.||||:|||..|..|.::|:|.||.|||:::|:|
Mouse   209 CANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTI 273

  Fly   251 HTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYH 315
            |.||||:||:.|.:|||::|||||:||.||:||:|::.||.||..:|||||::|||..|| |..:
Mouse   274 HQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEY-GDQN 337

  Fly   316 EPMVEAVGNGKVAR----------------WSPPAVEGETTTTKTDTTS--GASSFYERDQFDEE 362
            ..:|.||..|....                |..||.|        |:.|  |..||
Mouse   338 SRLVRAVREGMCDADYKRDLGGDTDVNPFLWHRPAEE--------DSASMEGCHSF--------- 385

  Fly   363 ISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFN 427
                  .|.|  ..|:.:|..|..:.:.||.....|:...:|.:.||:|.||.|:|..|.|.|.|
Mouse   386 ------SASC--LTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSN 442

  Fly   428 FGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLS 492
            .||:|..::..::..:||.:|.||.|:::..||:.|.||.|.:||.|...:.:|...:..|.|.|
Mouse   443 SGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCS 507

  Fly   493 IVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLI-SSRLSLVNAMFMGPVLAVPLILLSIYGI 556
            |||.|:|||.:..||.:...:..:|:|.:.|.|||| ::..||..|.|:|||.|:|::|.|.:.:
Mouse   508 IVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFV 572

  Fly   557 GYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFEN 621
            .:   ..|...::::.::||:|:..||::.|:|...|.|..|:..|. |.|:||:.:|..|..||
Mouse   573 SF---DTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAET-CHFQKSEAILRELDVEN 633

  Fly   622 MHYLWSLSCLMSFYLLFTVAAYFMIRLRLK 651
            .........|..|::...:.|||::|.:::
Mouse   634 AKLYLDFIVLGIFFISLRLIAYFVLRYKIR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	119/226 (53%)
		3a01204	67..654	CDD:273361	241/606 (40%)
		ABC2_membrane	381..587	CDD:279410	72/206 (35%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	252/636 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2712
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.760