Protein Alignment CG4822 and abcg8

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001108041.3
• Gene: abcg8 / 100136850
• ZFINID: ZDB-GENE-050517-41
• Length: 676
• Species: Danio rerio
• Alignment Length: 694
• Identity: 175/694 - (25%)
• Similarity: 319/694 - (45%)
• Gaps: 86/694 - (12%)

  Fly     7 VKG-----STTSQISSLQYSSDINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELC-YVVPD 65
            :||     |:..:.|||.::.....:.||         |..|.|.....|....:.:|. :.:|.
Zfish    21 IKGRDILFSSPEEDSSLYFTYSGGRNELE---------VRNLNYEVDTAAQIPWYEKLSEFKMPW 76

  Fly    66 QTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA--GFGAVCESGEILVNNSPRDMR 128
            :.:::| :|:::.:|...||.::.|:||.||.|||:||:::.  ..|....|||||:|..|....
Zfish    77 EMHSNK-QTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGGSMNSGEILINGKPSTRS 140

  Fly   129 VFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNT---- 189
            :.:|...::.|.|.|....||.|.:...|.|:|....:.||:.:.:|:::..|||:...:|
Zfish   141 LVKKSIAHVRQDDRLLPHLTVRETLAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVGN 205

  Fly   190 -MAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTP 253
             ..:.:|||||:|:.||::|:.||.::.|||||:|||..::...:..|..||.|.|.|:.|:|.|
Zfish   206 EYVRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRLARGNRLVLLSVHQP 270

  Fly   254 SAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFII------------EVA 306
            .:.||::.|.|.:|:.|..||.|:..::|.:....|..||...||:|:.:            |..
Zfish   271 RSDIFQLFDLVVLLSSGSAVYCGQAKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPEKEAQ 335

  Fly   307 CLEYGGSYHEPMVEAVGNGKVARW-----SPPAVEGETTTTKTDT--TSGASSFYERDQFDEEIS 364
            |||.........:|.|.|.:...|     .|||:|...::..:.:  .|..:...::||...::.
Zfish   336 CLEKASMLAAQFLEKVKNNEDFMWKSEVCGPPALEAPQSSVPSVSMKESVITVSKQKDQLPGKVH 400

  Fly   365 PKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFG 429
                        |:..|:.|.:...:||...:.:.....::::||:|.||||....        |
Zfish   401 ------------QFTTLIRRQVFNDYRDLVTLVVHGLEALLMSLLIGFLYFGCTEE--------G 445

  Fly   430 FMFTIVIAYLYL--------PMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFIL 486
            ......:|.||:        .::.|:....:|..:|..|..:..|.::.|:.|.|..:||.....
Zfish   446 LSIQDTVALLYMIGALTPFAVVLDVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELPEHCAF 510

  Fly   487 AVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRL-SLVNAMFMGPVLAVPLIL 550
            .::|...:|.::...:...||.:.|.:.::|...|.|..|.:::.| :|..:.|||..|.....|
Zfish   511 TLVYGVPIYWLAGLNVAPDRFLLNFLLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTVFYL 575

  Fly   551 LSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRAD-TICEDTEIFCSFKKSKVLL 614
            .:.:.|.......::   .:..::|::|...||::...:...|.. ||...|..|...|..:::
Zfish   576 TAGFVISLENMWMVA---SWFSYISFMRWGFEGMLQVQFRGTRIPITIGNLTVEFDGIKVVEMM- 636

  Fly   615 AFLGFENMHYLWSLSC---LMSFYLLFTVAAYFMIR-LRLKHSE 654
                  .|:.....||   |::..|:|.:..|..:: ::.|.|:
Zfish   637 ------KMNQYPLFSCYLVLIAVSLVFILLYYLSLKFIKQKSSQ 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	160/626 (26%)
abcg8	NP_001108041.3	None