Protein Alignment Nhe1 and NHX6

DIOPT Version :9

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_178079.2
• Gene: NHX6 / 844299
• AraportID: AT1G79610
• Length: 535
• Species: Arabidopsis thaliana
• Alignment Length: 571
• Identity: 192/571 - (33%)
• Similarity: 295/571 - (51%)
• Gaps: 71/571 - (12%)

  Fly    79 ASTLVTDPPLIDSHAVE-QEHNSSLSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFI 142
            :|.|...|.:.|....| |:..:.:.:...|.:::|..:|.|.:.:..|.||||:...:.:|..:
plant     2 SSELQISPAIHDPQGQEKQQQAAGVGILLQIMMLVLSFVLGHVLRRHKFYYLPEASASLLIGLIV 66

  Fly   143 GLSLNVMSGQNG--SWKREEVFSPMGFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTI 205
            |...|:.:.:..  :|..   |....|||.|||||||:||::|....||.|.|:|:.|::.||.:
plant    67 GGLANISNTETSIRTWFN---FHDEFFFLFLLPPIIFQSGFSLQPKPFFSNFGAIVTFSVLGTFV 128

  Fly   206 SALVIGAGIYLLGLGEVAFRLSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGESILN 270
            :::|.|..:||.|:..:.:||.|.|...|||||||.|||..::||..|..|..|..||||||:||
plant   129 ASMVTGLLVYLGGVMFLMYRLPFVECLMFGSLISATDPVTVLSIFQELGSDVNLYALVFGESVLN 193

  Fly   271 DAISIVL--TASITQSANVNAEASTGEAMFSALKTFCAMFFA--SAGIGVIFALISALLLKH--I 329
            ||::|.|  |.|:.:|      .|:|:..|..:..|...|..  |||:||.|.  ||||.|:  :
plant   194 DAMAISLYRTMSLVRS------HSSGQNFFMVIVRFLETFVGSMSAGVGVGFT--SALLFKYAGL 250

  Fly   330 DLRKHPSLEFAMMLMFTYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTL 394
            |:....:||..:.::|.|..|:||||:.||||::|||.||||.|||:.|||..:|..:......:
plant   251 DVDNLQNLECCLFVLFPYFSYMLAEGLSLSGIVSILFTGIVMKHYTYSNLSANSQRFVSAFFHLI 315

  Fly   395 AFIAETCVFAYLGLAIFSFKHQ-VELSFVIWAIVLCLIGRACNIFPLAFLVNKFR--EHKINNKM 456
            :.:|||.||.|:|..|...||. ..|.|:.::|:..:|.||.|:|...:|||..|  ..||....
plant   316 SSLAETFVFIYMGFDIAMEKHSWSHLGFIFFSILFIVIARAANVFGCGYLVNLARPAHRKIPMTH 380

  Fly   457 QFIMWFSGLRGAISYALSLHLNLDSQEKR-HVIITTTLIIVLFTTLVLGGSTMPLLKYLKPGKKR 520
            |..:|:||||||:::||:|....|..|.. ..|.|.|..||:.|.|::||||..:|:.|:.
plant   381 QKALWYSGLRGAMAFALALQSVHDLPEGHGQTIFTATTAIVVLTVLLIGGSTGTMLEALEV---- 441

  Fly   521 RARGSGRNAAEEGGRRNGSGRKRSKSISLSKTREWGQAIDSEHLSELTEEEDV----------TF 575
                              .|.....|:.     :..:.::|.:::...:|:..          .|
plant   442 ------------------VGDSHDTSLG-----DGFEVVNSRYMTSYDDEDTPPGSGFRTKLREF 483

  Fly   576 TQARDRFGRMDRKYFIPFFTR-------RFNSQELHECK---SQMADLTNK 616
            .::...|..:||.|..||||.       ..|.::.||.:   ::..:|.|:
plant   484 HKSAASFTELDRNYLTPFFTSNNGDYDDEGNMEQHHEERIPFTRRGNLNNR 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	NhaP	100..515	CDD:223104	167/426 (39%)
NHX6	NP_178079.2	NhaP	23..446	CDD:223104	169/455 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	263	1.000	Domainoid score	I471
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H75041
Inparanoid	1	1.050	271	1.000	Inparanoid score	I916
OMA	1	1.010	-	-		QHG55694
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3053
orthoMCL	1	0.900	-	-		OOG6_100371
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3978
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.770