Protein Alignment Nhe1 and NHX5

DIOPT Version :10

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_175839.2
• Gene: NHX5 / 841878
• AraportID: AT1G54370
• Length: 521
• Species: Arabidopsis thaliana
• Alignment Length: 514
• Identity: 180/514 - (35%)
• Similarity: 277/514 - (53%)
• Gaps: 32/514 - (6%)

  Fly    94 VEQEHNSSLSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFIGLSLNVMSGQNG--SW 156
            |:|:..:.:.:...|.:::|..:|.|.:.:..|.||||:...:.:|..:|:..|:...:..  :|
plant    17 VKQQQAAGVGILLQIMMLVLSFVLGHVLRRHRFHYLPEASGSLLIGLIVGILANISDTETSIRTW 81

  Fly   157 KREEVFSPMGFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTISALVIGAGIYLLGLGE 221
            ..   |....|||.|||||||:||::|....||.|.|:|:.|||.||.::::|.|..:||.|...
plant    82 FN---FHEEFFFLFLLPPIIFQSGFSLQPKPFFSNFGAIVTFAIIGTFVASVVTGGLVYLGGSMY 143

  Fly   222 VAFRLSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGESILNDAISIVL--TASITQS 284
            :.::|.|.|...||:||||.|||..::||..:..|..|..||||||:||||::|.|  |.|:
plant   144 LMYKLPFVECLMFGALISATDPVTVLSIFQDVGTDVNLYALVFGESVLNDAMAISLYRTMSL--- 205

  Fly   285 ANVNAEASTGEAMFSALKTFCAMFFA--SAGIGVIFALISALLLKH--IDLRKHPSLEFAMMLMF 345
              ||.::|:||..|..:..|...|..  |||:||.|.  ||||.|:  :|.....:||..:.::|
plant   206 --VNRQSSSGEHFFMVVIRFFETFAGSMSAGVGVGFT--SALLFKYAGLDTENLQNLECCLFVLF 266

  Fly   346 TYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTLAFIAETCVFAYLGLAI 410
            .|..|:||||:.||||::|||.||||..||..|||..:|..:......::.:|||..|.|:|..|
plant   267 PYFSYMLAEGVGLSGIVSILFTGIVMKRYTFSNLSEASQSFVSSFFHLISSLAETFTFIYMGFDI 331

  Fly   411 FSFKHQ-VELSFVIWAIVLCLIGRACNIFPLAFLVNKFRE--HKINNKMQFIMWFSGLRGAISYA 472
            ...:|. ..:.|::::|:...:.||.|:|..|:|||.||:  .||..|.|..:|:||||||:::|
plant   332 AMEQHSWSHVGFILFSILFIGVARAVNVFGCAYLVNLFRQENQKIPMKHQKALWYSGLRGAMAFA 396

  Fly   473 LSLHLNLDSQEKR-HVIITTTLIIVLFTTLVLGGSTMPLLKYLKPGKKRRARGSGRNAAEEGGRR 536
            |:|....|..|.. .:|.|.|..||:.|.|::||||..:|:.|:      ..|...:.:...|..
plant   397 LALQSLHDLPEGHGQIIFTATTTIVVVTVLLIGGSTGKMLEALE------VVGDDLDDSMSEGFE 455

  Fly   537 NGSGRKRSKSISLSKTREWGQAIDSEHLSELTEEEDVTFTQARDRFGRMDRKYFIPFFT 595
            ....:......|:..:.:...:..........:|    |.:....|..:|:.:..||||
plant   456 ESDHQYVPPPFSIGASSDEDTSSSGSRFKMKLKE----FHKTTTSFTALDKNFLTPFFT 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	Na_H_Exchanger	111..597	CDD:470090	177/497 (36%)
NHX5	NP_175839.2	Na_H_Exchanger	27..>445	CDD:470090	168/433 (39%)