DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nhe1 and NHX4

DIOPT Version :10

Sequence 1:NP_608491.3 Gene:Nhe1 / 33167 FlyBaseID:FBgn0026787 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_001327377.1 Gene:NHX4 / 819811 AraportID:AT3G06370 Length:552 Species:Arabidopsis thaliana


Alignment Length:455 Identity:152/455 - (33%)
Similarity:254/455 - (55%) Gaps:53/455 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 EHNSSLSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFIGLSLNVMSGQNGSWKREEV 161
            :|.|.:|:...:.::...|:|.|.:.:|  :::.|||..:.:|:..|:.:.::||  |...|..|
plant    19 DHASVVSMNLFVALLCACIVLGHLLEET--RWMNESITALIIGSCTGIVILLISG--GKSSRILV 79

  Fly   162 FSPMGFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTISALVIGAG----IYLLGLGEV 222
            ||...||:.|||||||.:|:.:.|..||:|..:|::|...||.||.::|..|    ...:.:|: 
plant    80 FSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFMTIMLFGAIGTLISFVIISFGAKHLFEKMNIGD- 143

  Fly   223 AFRLSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGESILNDAISIVLTASITQ--SA 285
               |:.::..|.|::.||.|.|.|:.:.:. |..|:|..|||||.::|||.|:||..:|.:  ..
plant   144 ---LTIADYLAIGAIFSATDSVCTLQVLNQ-DETPLLYSLVFGEGVVNDATSVVLFNAIQRFDLT 204

  Fly   286 NVNAEASTGEAMFSALKTFCAMFFASAGIGVIFALISALLLKHIDLRKHPS-LEFAMMLMFTYAP 349
            |:|:..:...|     ..|..:|..|..:||...|:||.::|.:.:.:|.: .|.|:|::..|..
plant   205 NINSAIALEFA-----GNFFYLFILSTALGVAAGLLSAFVIKKLYIGRHSTDREVALMMLLAYLS 264

  Fly   350 YVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTLAFIAETCVFAYLGLAIFSFK 414
            |:|||..|||.|:.:.||||||||||..|::..:::|.:.|...::|:||..:|.|:|:.....:
plant   265 YMLAELFHLSSILTVFFCGIVMSHYTWHNVTDKSKVTTKHTFAAMSFLAEIFIFLYVGMDALDIE 329

  Fly   415 HQVELSFVIWAIV----------------LCLIGRACNIFPLAFLVNKFR---EHKINNKMQFIM 460
            .        |.:|                |.|:|||..:|||:||.|..:   :.||:.|.|..:
plant   330 K--------WDVVRNSPGQSIGVSSILLGLILLGRAAFVFPLSFLSNLTKSSPDEKIDLKKQVTI 386

  Fly   461 WFSGL-RGAISYALSLHLNLDSQEKR----HVIITTTLIIVLFTTLVLGGSTMPLLKYLKPGKKR 520
            |::|| |||:|.||:.:....|...:    .::||:|:.:|||:|:|.|..|.||:|:|:|..|:
plant   387 WWAGLMRGAVSMALAYNQFTTSGHTKVLGNAIMITSTITVVLFSTVVFGLLTKPLVKHLQPSSKQ 451

  Fly   521  520
            plant   452  451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nhe1NP_608491.3 Na_H_Exchanger 111..597 CDD:470090 149/441 (34%)
NHX4NP_001327377.1 Na_H_Exchanger 46..>470 CDD:470090 146/428 (34%)

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