Protein Alignment Nhe1 and slc9a6a

DIOPT Version :9

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_009289416.1
• Gene: slc9a6a / 792983
• ZFINID: ZDB-GENE-070424-104
• Length: 732
• Species: Danio rerio
• Alignment Length: 524
• Identity: 168/524 - (32%)
• Similarity: 268/524 - (51%)
• Gaps: 98/524 - (18%)

  Fly    82 LVTDPPLIDSHAVEQEHNSSLSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFIG--- 143
            :||:....:||     ...|..|...|.::.|.||.|.......|::|.|:.:.:..|..:|
Zfish    45 IVTEKKAEESH-----RQDSADLLIFIMLLTLTILTIWLFKHRRFRFLHETGLAMIYGLLVGVVL 104

  Fly   144 -------------------------LSLNV--------MSGQNGSWK----------REEVFSPM 165
                                     |.:||        :.|:.|:.|          |:..|.|.
Zfish   105 RYAIHVPSDINNVTLSCHVNASPATLLVNVSGKFYEYTLKGEIGANKVNDIQDNEMLRKVTFDPE 169

  Fly   166 GFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTISALVIGAGIY-----LLGLGEVAFR 225
            .||.:|||||||.:||:|.:.:||:|:||||.:|..||.:|..:|||.:|     :..:|.:...
Zfish   170 VFFNILLPPIIFHAGYSLKRRHFFRNLGSILAYAFVGTVVSCFIIGALMYGCVMLMKKIGHLQDD 234

  Fly   226 LSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGESILNDAISIVLTASI--------- 281
            ..|::...||:::||.|||..:|||:.|.||..|..|:||||:||||:::||::.:
Zfish   235 FFFTDCLFFGAIVSATDPVTVLAIFNELQVDADLYALLFGESVLNDAVAVVLSSMLLYYGRQSGA 299

  Fly   282 ----------------TQSANVN----AEASTGE--------AMFSALKTFCAMFFASAGIGVIF 318
                            ||...:|    |...||:        ||..:...|..:|..|..:||..
Zfish   300 GHHSPGGVAYAEGGNQTQRPPLNGSIVAYQPTGDNSHTFEAMAMLKSFGIFLGVFSGSFALGVAT 364

  Fly   319 ALISALLLKHIDLRKHPSLEFAMMLMFTYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVT 383
            .:::||:.|...||..|.||.|:..:.:::.::|||....:|::|:||||:..:|||..|||..:
Zfish   365 GIVTALVTKFTKLRDFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGMTQAHYTFNNLSPES 429

  Fly   384 QITMQQTMRTLAFIAETCVFAYLGLAIFSFK-HQVELSFVIWAIVLCLIGRACNIFPLAFLVNKF 447
            |...:|....|.|:||..:|:|:||.:|:|: |.....|::.|.:...:|||.||:||:||:|..
Zfish   430 QDRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPIFIVCAFLAVFLGRAANIYPLSFLLNLG 494

  Fly   448 REHKINNKMQFIMWFSGLRGAISYALSLHLNLDSQE-KRHVIITTTLIIVLFTTLVLGGSTMPLL 511
            |.:||::..|.:|.|:|||||:::|||:.   |:.. .|.::.:|||::|.||..:.||.|..:|
Zfish   495 RRNKISSNFQHMMMFAGLRGAMTFALSIR---DTATYARQMMFSTTLLVVFFTVWICGGGTTQML 556

  Fly   512 KYLK 515
            ...|
Zfish   557 SCQK 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	NhaP	100..515	CDD:223104	163/504 (32%)
slc9a6a	XP_009289416.1	Na_H_Exchanger	164..556	CDD:279355	143/394 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D242793at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100371
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.720