Protein Alignment Nhe1 and pbo-4

DIOPT Version :9

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_509830.2
• Gene: pbo-4 / 181285
• WormBaseID: WBGene00003943
• Length: 783
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 164/585 - (28%)
• Similarity: 277/585 - (47%)
• Gaps: 107/585 - (18%)

  Fly    94 VEQEHNSS------------------LSLFFVICVIMLGILLIHSMLQTGFQYLPESIVVVFLGA 140
            |..||:.|                  |:|||:  ||.|..|:.|....|. :.||||..::|:|.
 Worm    84 VGNEHDESHGISVVSWHWDYVKNELVLTLFFI--VIGLFKLVYHHTFVTR-KILPESCCLIFIGI 145

  Fly   141 FIGLSLNVMSGQNGSWKREEVFSPMGFFLVLLPPIIFESGYNLHKGNFFQNIGSILVFAIFGTTI 205
            .||... |....:.|.|..| |....||..||||||.||.|:|....|.:|||:||::|:.||.:
 Worm   146 AIGFFF-VGDATHASIKFLE-FKSKVFFFYLLPPIILESAYSLKDRAFIENIGTILLYAVVGTIL 208

  Fly   206 SALVIGAGIYLL---G-LGEVAFRLSFSESFAFGSLISAVDPVATVAIFHALDVDPILNMLVFGE 266
            :.:::.|.:.:|   | :|:  :.||..:...|.||::||||||.:|:|..:.|:.:|..:||||
 Worm   209 NIVLLAAALLILIWVGIMGK--YNLSVMDILTFASLVAAVDPVAVLAVFQEVGVNKMLYFMVFGE 271

  Fly   267 SILNDAISIVLTASITQSANVNAEAST--------GEAMFSALKTFCAMFFASAGIGVIFALISA 323
            |:.|||::||       ..|:..|..|        |   |..|.:|..:......||:|...||:
 Worm   272 SLFNDAVTIV-------CYNLAIEFQTLPDFTWYHG---FLGLLSFLCVSIGGLIIGLICGAISS 326

  Fly   324 LLLKH-IDLR-KHPSLEFAMMLMFTYAPYVLAEGIHLSGIMAILFCGIVMSHYTHFNLSTVTQIT 386
            .:.|. .|:| ..|.:.|.|    .|..|:.:|..|.|||:|::.||:..:||...|:|..:..:
 Worm   327 FVTKFTTDVRVVEPVVLFGM----AYLAYLGSEMFHFSGIIALIACGLFQTHYACCNISYKSFTS 387

  Fly   387 MQQTMRTLAFIAETCVFAYLGLAIFSFK-------HQVELSFVIWAIVLCLIGRACNIFPLAFLV 444
            :....:..:.:.|:.:|..||:.:.:.:       |.|   |...::|||::.|....|.|.:.|
 Worm   388 VMYITKVCSTLCESLIFIILGVMLVNEREWFWTDWHPV---FSAVSVVLCVVVRFGVTFFLTYFV 449

  Fly   445 NKFR---EHKINNKMQFIMWFSGLRGAISYALSLHLNLDSQEKRHVIITTTLIIVLFTTLVLGGS 506
            |:|.   .| |:.:.||||.:.|||||:|::|...::.:...| :.::..|..::|||.::.|.:
 Worm   450 NQFTGGVRH-ISFQEQFIMSYGGLRGAVSFSLVFMISANPDVK-NTMLGATYAVILFTNIIQGST 512

  Fly   507 TMPLLKYLKPGKKRRARGSGRNAAEEGGRR------NGSGRKRSKSISLSKTREWGQAIDSEHLS 565
            ....:|:|          :.|.|.:|...|      ||..:..|:.|                 .
 Worm   513 IKLFVKWL----------NIRLAKKEDHFRLFIEFNNGMVQHLSQGI-----------------E 550

  Fly   566 ELTEEEDVTFTQARDRFGRMDRKYFIPFFTRRFNSQELHECKSQMADLTN--KWYQAIRVSPLDS 628
            :|..::.::..   :|...:.:||..|...:.:.:.:..: :.::.:|..  ...:|:..||..|
 Worm   551 DLCGDKSLSLI---NRMSELSKKYVRPLLEKNYTANKAKK-EGKLVELNRAVAMREALNNSPSQS 611

  Fly   629  628
             Worm   612  611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	NhaP	100..515	CDD:223104	142/456 (31%)
pbo-4	NP_509830.2	Na_H_Exchanger	115..519	CDD:279355	136/429 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810