Protein Alignment Nhe1 and slc-9B.1

DIOPT Version :9

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_509724.1
• Gene: slc-9B.1 / 181236
• WormBaseID: WBGene00009617
• Length: 516
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 95/497 - (19%)
• Similarity: 173/497 - (34%)
• Gaps: 146/497 - (29%)

  Fly    92 HAVEQEHNSSLSLFF---VICVIMLGILLIHSMLQTGFQYLPESIVVVFLGAFIGLSLNVMSGQN 153
            |.|.:.|| :|..||   .|..|...||:..|:      |:  ||:.:....|:....:.::..|
 Worm     2 HCVARLHN-TLHNFFNNREINSITTTILIFISL------YI--SIITLLGENFLNPLADHVNPVN 57

  Fly   154 GSWKREEVFSPMGFFLVL--------------LPPIIFESGYNLHKGNFFQNIGSILVFAIFGTT 204
            .:.:...|.|....|::|              |||:.   |. |..|...:||.....|.:|...
 Worm    58 ATNEDVTVRSIFVIFILLVAGIFAAKISKALRLPPLF---GC-LALGIIIKNITVFDQFFVFPPF 118

  Fly   205 ISALVIGAGIYLLGLGEVAFRLSFSESFAFGS--------LISAVDPV--ATVAIFHALDVDPIL 259
            :..::....:.::   .|.:.|:....|.:.:        |::|:..:  .|:|.:..|::.
 Worm   119 VETMIRKVALVMI---IVRWGLATDIHFLYENALMPVTIGLVTAIGEIIAVTIASYFILNIS--- 177

  Fly   260 NMLVFGESILNDAISIVLTASITQSANVNAEASTGEAMFSALK--------------TFCAMFF- 309
                |..||....|.:.::.::|..|.:|.:    |....:||              .||.:.|
 Worm   178 ----FVMSIFCALILVTVSPAVTVPAMINFK----EKQLGSLKRIPENILAICCVDNLFCVILFM 234

  Fly   310 -----------------ASAGIGVIFALISALLLKHIDLR----KHPSLEFAMMLMFTYAPYVLA 353
                             .:|| .::|..|..::|..|..|    ..|..:||.:.:.......:.
 Worm   235 VLSSIIFTDAPIATTILLNAG-SIVFGCIGGIVLGWILWRFPRSDAPHTQFARITLLGTICIAVV 298

  Fly   354 EGIHL-----SGIMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTLAFI----AETCVFAYLGLA 409
            .|.:|     ||.:|.|    :.|..:........:..::....|..:|    |...:|..||:
 Worm   299 IGTYLIKYSCSGFLAAL----ITSAMSAMQWKADNKEKLECVESTYKYIWDSFALPLLFICLGM- 358

  Fly   410 IFSFKHQVELSFVIWAIV-LCLIGRACNIFPLAFLVNKFREHKINNKMQFIMWFSGLRGAISYAL 473
                  :.:.|.:.|.|| ||:...|..:.....||                        :...|
 Worm   359 ------KFDCSTLTWEIVFLCIAVIAIGLLVRTILV------------------------MLVTL 393

  Fly   474 SLHLNLDSQEKRHVIITTTLI------IVLFTTLVLGGSTMP 509
            |.|:|.    |..:::..:|:      ..|..||:|..:..|
 Worm   394 SSHINF----KEQIVVALSLLPRATFQADLAPTLLLMATPFP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	NhaP	100..515	CDD:223104	91/489 (19%)
slc-9B.1	NP_509724.1	Na_H_Exchanger	68..455	CDD:382399	76/422 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900