Protein Alignment Nhe1 and slc9a2l

DIOPT Version :9

• Sequence 1: NP_608491.3
• Gene: Nhe1 / 33167
• FlyBaseID: FBgn0026787
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_031748023.1
• Gene: slc9a2l / 100488264
• XenbaseID: XB-GENE-6464693
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 164/550 - (29%)
• Similarity: 265/550 - (48%)
• Gaps: 81/550 - (14%)

  Fly   116 LLIHSMLQTGF-------QYLPESIVVVFLGAFIGLSLNVMSGQNGSWKREEVFSPMGFFLVLLP 173
            :::.|:.:.||       ..:|||.:::.:|..:|.   ::.|...  |...|.:...|||.|||
 Frog    84 IMLASLAKIGFHLSYKLPSVIPESCILIIVGLIMGA---IIYGVKD--KYVPVMNSDIFFLYLLP 143

  Fly   174 PIIFESGYNLHKGNFFQNIGSILVFAIFGTTISALVIGAGIYLLGLGEVAF----RLSFSESFAF 234
            ||:.::||.:....||:|||.||.:||.||..:  |:|.||.|.|:.:|..    .:|...:..|
 Frog   144 PIVLDAGYFMPSRPFFENIGPILWYAIVGTLWN--VLGIGISLYGICQVNVFGLQNISLLHNLWF 206

  Fly   235 GSLISAVDPVATVAIFHALDVDPILNMLVFGESILNDAISIVLTASITQSANVNAEASTGEAMFS 299
            ||||:||||||.:::|..:.|:..|.:||||||:||||:::|| ..:.::.:..||..    :..
 Frog   207 GSLIAAVDPVAVLSVFEEIHVNERLYILVFGESLLNDAVTVVL-YKLFEAFDKMAEIQ----LMD 266

  Fly   300 ALKTFCAMFFASAG---IGVIFALISALLLKHID-LRKHPSLEFAMMLMFTYAPYVLAEGIHLSG 360
            .|....|.|....|   .|:.|..::||..:..: :|   .:|...:.:::|..|:.||..||||
 Frog   267 ILVGIGAFFIVGIGGVLFGLAFGFVAALTTRFTENIR---VIEPLFVFLYSYLCYLTAEMFHLSG 328

  Fly   361 IMAILFCGIVMSHYTHFNLSTVTQITMQQTMRTLAFIAETCVFAYLGLAIFSFKHQVELSFVIWA 425
            |:||:.|.:.|..|...|:|..:..|::..|:..:.::||.:|.:||::.....|:....|:...
 Frog   329 IVAIIACSMSMKRYVESNISQKSYTTVKYFMKMWSSVSETLIFIFLGVSTIGDNHEWNWPFISLT 393

  Fly   426 IVLCLIGRACNIFPLAFLVNKFREHKINNKMQFIMWFSGLRGAISYALSLHLNLDSQEKRHVIIT 490
            :|.|:..||..:..|.|::|||..:.|..|.|||:.:.||||||.:  ||...|....|:.:.||
 Frog   394 LVFCISWRAFGVIVLTFVLNKFCLNSITKKDQFIIAYGGLRGAICF--SLVFLLPEFPKKQLFIT 456

  Fly   491 TTLIIVLFTTLVLGGSTMPLLKYLKPGKKRRARGSGRNAAEEGGRRNGSGRKRSKSISLSKTREW 555
            .|.:::|||..|.|.:..||::.|...|..|                          ::|...|.
 Frog   457 ATTVVILFTVFVQGMTIRPLVELLDVKKSNR--------------------------NISTVSEQ 495

  Fly   556 GQAIDSEHLSELTEEEDVTFTQA----RDRFGRMDRKYFIPFFTRRFNSQELHECKSQMADLTNK 616
            ......:||  :|..|||.....    :|:|...:.||......|.      ::.||.:..|..|
 Frog   496 VHIRFLDHL--VTGIEDVCGHWGQYYWKDKFEYFNNKYLRKILLRD------NQTKSSIVLLYEK 552

  Fly   617 WYQAIRVSPLDSDESDE--EIGLAASTSQI 644
                     |:...:.|  |.|..:..|||
 Frog   553 ---------LEKKHAIELAEAGQLSDISQI 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe1	NP_608491.3	NhaP	100..515	CDD:223104	137/413 (33%)
slc9a2l	XP_031748023.1	b_cpa1	71..623	CDD:273294	163/549 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D546232at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920