DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11377 and LOC100003741

DIOPT Version :9

Sequence 1:	NP_608490.1	Gene:	CG11377 / 33166	FlyBaseID:	FBgn0031217	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_009304516.1	Gene:	LOC100003741 / 100003741	-ID:	-	Length:	234	Species:	Danio rerio

Alignment Length:	257	Identity:	68/257 - (26%)
Similarity:	101/257 - (39%)	Gaps:	74/257 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 LTVCCPLNTYGPDCLTCTECNGNGKCKGDGTRKGNGKCKCDPGY------------AGPNCNECG 179
            |:|.....|:|.:|        :..||..|..:.|...:|..|:            .|.:.::|
Zfish    11 LSVALSHLTWGQNC--------SDHCKACGGPENNQCLQCQTGFILHDNLCVDIDECGTDLDQC- 66

  Fly   180 PEHYESFRDEKKLLCTQCHAACGEGGCTGGGPKSCRKCKKGWSMDSEAGCVDINECLEQQRPNPC 244
            |.:...|.......|..|..||  .||.|||...|:||..|: ..|...|:|::||.|:..  .|
Zfish    67 PHNTYCFNTRGSYECKGCDKAC--VGCMGGGAARCKKCAPGY-RSSGLRCMDVDECGEEVL--AC 126

  Fly   245 RP-QQFCVNNEGSFSCLECDRSCDGCDGDGPDMCRKCADGYELKEGKCH----DISAE------- 297
            .. ..||||.||||.|                   :||:|:..:|..|.    ..|||
Zfish   127 AGLNVFCVNTEGSFQC-------------------QCAEGFTRREQNCERQQTSASAEKGLFDDI 172

  Fly   298 QRSNYVSFTRMLTYFGMCVATCVIFQSSTHIAWGCIV------GAAVAGYIAVSEYWINSEA 353
            |....:...:|  :||  |..|.:   :|..|.|.:|      |||.    |::.||::.::
Zfish   173 QEDELMVLQQM--FFG--VVLCAL---ATLAAKGDLVFTSIFMGAAA----AMAGYWLSDKS 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11377	NP_608490.1	DUF3456	31..123	CDD:288766
		EGF_CA	231..>259	CDD:214542	13/28 (46%)
		FU	258..293	CDD:214589	6/38 (16%)
LOC100003741	XP_009304516.1	FU	24..>71	CDD:238021	10/55 (18%)
LOC100003741	XP_009304516.1	vWFA	<113..154	CDD:294047	19/61 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378427at33208
OrthoFinder	1	1.000	-	-		FOG0002526
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920