|
Fly 5 QRSFVQKVSKQSAADVRKNVSGCH-----------------------LSKAMDPSLCGSSISPTE 46
:|:|.||:|:..||:|||.:||.: |::|:|
Mouse 4 RRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVD------------ 56
Fly 47 PLDYEEFLSQHMNIINRDPLKHILDFPQGDVTVKIIPRKIRTVDHVVPNENLSDLPHHVQECVNC 111
|:|.|::|..|....:..||:.:::||..|:.|...||..||:...||.| |::..||::|:..
Mouse 57 PVDLEDYLVTHPLSGDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEE--SEMDPHVRDCIRS 119
Fly 112 YTRPWKVVEYAQRHLSSSCYIRERIDRGT-ISPSAYQQEFEIDKD-----FSSFE--EAFAYKSE 168
||..|.|| :|:....|| .:|:...::.|..|. |.|.| :..:|:.|
Mouse 120 YTEDWAVV------------VRKYHKLGTGFNPNTLDKQKERQKGLPRQVFESDEAPDGSSYQDE 172
Fly 169 SCTPSSRQSIASLASVSSCTDTLTPRGSWAS--FDLRRSVNDPLIPNLLDNVPPEHIDQSNEARR 231
. ....|:|: |..| |||||||. |||:.|:.|.|:|||||..|.|.||..|:.:|
Mouse 173 Q-DDLKRRSM-------SIDD--TPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDHQNDDQR 227
Fly 232 QQDRQMALFSLYPESEAEENIERRLLAEIPVEHMGHRIQVNCLQLRLELEVEPIFASMAIYDAKE 296
:.:|...||:|:|..:.||.|||..:.::|.||.|.|:.|.||.|:.|:|:||||||:|:||.||
Mouse 228 KSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKE 292
Fly 297 RQKISENFYFDMNADSLKRMLSSHVQCADISTQSHSAIFEISYPSNDLFLVIRLEKVL-QGDINN 360
::|||||||||:|::.:|.:|..||..|.|:|.:.||||.|:|||.|:||||:||||| ||||..
Mouse 293 KKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGE 357
Fly 361 SVEPYL--KE-----DKDKYREKVKSNAVDYCERLGKYRMPFAWTGIYLTNVFNGDNFESKDAGA 418
..|||: || :|:|. ||:||.|..:|:||||||||||||.|:|.|:.: .||:
Mouse 358 CAEPYMIFKEADATKNKEKL-EKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVS-------SAGS 414
Fly 419 AERDSFGNACGSSLGTAPSSNSLDRKSSTSSFDQLRRKANDMSGTLTRRGSLERKEKHRSWSPDD 483
.|||| |....::.:||.|.|. || :.:|..|.||| |:.|.||
Mouse 415 LERDS----------TEVEISTGERKGSWSE----RR-----NSSLVGRRSLE-----RTTSGDD 455
Fly 484 FANVVENFRPITITVPSFFKQEADKMKDEDLYKILPELKRPSSVMKKYKCIPGSIKLEISPCVEE 548
..|:. :|||.|:||.:|||||.|::.||||||.|.:::|||||:::.:.|...:|::|||..|.
Mouse 456 ACNLT-SFRPATLTVANFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPEN 519
Fly 549 AKNALTPELAPINPQSADNVRPVKEILEFPQSAIYNPHYSYRNLLFVSPKELNFSSRAGSARNIA 613
....|||||..:.......|||.:||||||...:|.|:.:|||||::.|:.|||::|.||||||.
Mouse 520 PHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNIT 584
Fly 614 VRVQLMAGETPKDAVNAIYGKSSCPKFSTEAFTAVNYHNKCPSFYDEIKIALPASIKQHHHLLFT 678
|:||.|.||.|.:|:..|:|||||.:||.||:|||.|||:.|.|::|||:.|||::..|||||||
Mouse 585 VKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFT 649
Fly 679 IYHVSCQKKPQDLQPSVETPIGYTWLPLLEDGKLKFGEFNLPVMVESPPENYSFIPPNVHLPGIK 743
.||||||:|. ...:|||:||||:|:|::|:||.|:|.|||.:|.||:.||.:.|.|.|||:|
Mouse 650 FYHVSCQQKQ---NTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMK 711
Fly 744 WLDNHRAVFSINVEAVTAIHTLDSFLDRFFLICEYLDTRNIPSHIG-----ENNIETELKKCLLD 803
|:|||:.||::.|.||::|||.|.:||:||.:...||....|..|| |||:|:|||..:..
Mouse 712 WVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISA 776
Fly 804 IEYANREPLVRHLPLVLDKLIELLVVTHKVGGQAMSLGSTVFEVLCLVSSLLSILNDDQYDQYGR 868
:..:..||:||.|.|:|||||.|:|....:.||.::||...||.:..:.:.|....:..:||:||
Mouse 777 LNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGR 841
Fly 869 QSLLSTYVHFQCKIPHPFQ------------SKQRLTCSRSTTE--DLQLSESYTIY-------- 911
.:||::|:::..::|:.:. |....|.:||... .|.|:.|.::.
Mouse 842 NNLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISG 906
Fly 912 ------DNV--LASGRSLDRKELSIDV-------------------------------------L 931
|.| :...:.|||....::. |
Mouse 907 TPTSPDDEVRSIIGSKGLDRSNSWVNTGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFL 971
Fly 932 HSMAAR------------DVQVRLLHEELALHWVVASGKAADLAMSNSWFLFELIVKSMIEHLHC 984
.::..| .:.:.|.||||||.|||.||...:.|:..:||.|||:||||:.||:.
Mouse 972 QTLTGRLPTKKGKEDELEKLSLLLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYF 1036
Fly 985 SNTLNGPRKHRFPHQFNDDLSTLVHLVTTKVVGYHSNEPKLAQSLNASLGFFIFDILSIMDRGFV 1049
::.|:.|||.|||.:|.||::.||..:...||.....:.::.:.||.||.||:.|:||:||||||
Mouse 1037 NDKLDAPRKSRFPERFMDDIAALVSTIAGDVVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFV 1101
Fly 1050 FGLIKTYTKVLISKNASIPD---LMNYKIDFLRIVCSHEHFVALNLPFGTSYTMVTAPCSPTPST 1111
|.|||:..|.:.:|..|:|: |::.::|||||:|||||:|.|||| .:::|.|.||:||.
Mouse 1102 FSLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLP----CSLLTPPASPSPSV 1162
Fly 1112 TSSNSQ-----TSCGSLERALHADLSQEFLQQHFLVGLVLSDLAAVMEVPNPQ----LHGKAIRC 1167
:|:.|| ||....:.|...:||..|.|||:|.||||::||.::: |:.: ||.|.|..
Mouse 1163 SSATSQSSGFSTSVQDQKIANMFELSLPFRQQHYLAGLVLTELALILD-PDAEGLFGLHKKVINM 1226
Fly 1168 IRNLMTSHDLDARYSETDARARVAALYIPLLSIVMDCIPQLHQHGLEQDRLQQIGQ-----LEDY 1227
:.||:::||.|.|||:...:||||.||:||:.|:|:.:|||:.. .:...|.|: .:||
Mouse 1227 VHNLLSTHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDF---TESHNQRGRPICIAPDDY 1288
Fly 1228 QGPHQTITASTINPEVAFAISG------SRPYSYL--NEQVKNKLPLSSENTRHLLVCFLWVLKN 1284
... :.|.|:..||.||:| :||.|:| :...:.....|:|::|.||:|.||||||
Mouse 1289 DSE----SGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKN 1349
Fly 1285 LERNVLYRWLMDLSPHRVHQMLQGVNVCLKTFEYTGQKNVATLKRTNTQSFRKTGSTDVKEKLEE 1349
.:..||.:|..|||..:::::|..:.:|:..|||.|:| ..:|.|:.:|:| |.|::.||||
Mouse 1350 ADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKK---VFERMNSLTFKK--SKDMRAKLEE 1409
Fly 1350 CIRGTNSARYDLINRRKDR----------NSTEKFRWRKDQMPYRSQYADAVGKSEHELELSHFI 1404
.|.|:..||.:::.|.:.: .|.|..|||||...:| |.::.:.||..|:|....|
Mouse 1410 AILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWR-QNSEKLDKSRAEIEHEALI 1473
Fly 1405 EGSLATEVALVLLDTLEIIVH--AAANLYHNLLGTVLKVLLHSLSRNQSVLALQNLFASQRALIF 1467
:|:||||..|::||||||||. :......::||.||||||.|::.|||.:.||:.||:||||:.
Mouse 1474 DGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLQSMACNQSAVYLQHCFATQRALVS 1538
Fly 1468 KFPNLLFDDETDICADLCLILLKHCGSLLPGIRSQAAASLYLLMRQNFEIGNNFARVKMQVTMSL 1532
|||.|||::||:.||||||.||:||.|.:..|||.|:||||||||||||||||||||||||||||
Mouse 1539 KFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSL 1603
Fly 1533 SSLVGTSSVFSEQSLRRALKTVLVYAESDSDLQDTSFPEQVQDLLFNLHMILSDTVKMKEYQEDP 1597
|||||||..|:|:.|||:|||:|.|||.|.:|::|:||:|||||:|||||||||||||||:||||
Mouse 1604 SSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDP 1668
Fly 1598 EMLLDLMNRIAKGYQNNPDLRLTWLENMAKKHRERANHTEAAMCYVHAASLVSEYLSMLESQKHL 1662
|||:|||.|||||||.:||||||||:|||.||.||:||.|||.|.||:|:||:|||||||.:|:|
Mouse 1669 EMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYL 1733
Fly 1663 PVGAVSFQRISPNTLMESAVSDDVLSPGEDGICLGNHFTETGLKALLEEASNSFQVAGMYEAMNE 1727
|||.|:||.||.|.|.||||||||:||.|:|||.|.:|||:||..|||:|:.||.:||||||:||
Mouse 1734 PVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNE 1798
Fly 1728 VYKILIPICEANRDFQKLSKVHGKLQEAFNRI-SQLQG-KRVFGTYFRVGFYGGKFGDLDQQEFI 1790
|||:||||.|||||.:|||.:||||||||::| .|..| :|:|||||||||||.||||||:|||:
Mouse 1799 VYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFV 1863
Fly 1791 YKEPTLTKLPEIFSRLQNFYTERFGPDSVHIIKDSNTVDINSLDPDKAYIQITYVEPYFETYEMR 1855
||||.:|||.||..||:.||.||||.|.:.:|||||.||...|||:|||||||||||:|:||||:
Mouse 1864 YKEPAITKLAEISHRLEGFYGERFGEDVLEVIKDSNPVDKCKLDPNKAYIQITYVEPFFDTYEMK 1928
Fly 1856 HRETYFERNFNIKRFIYATPFTKNGKAHGELNEQCKRKTILTTANHFPYVKTRIMVISRQQIVLE 1920
.|.|||::|:|::||:|.||||.:|:|||||:||.||||||||::.|||:|||:.|..:::|:|.
Mouse 1929 DRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILT 1993
Fly 1921 PIEVAIEDIQKKTLELAAATNQEPADPKILQMVLQGCIGTTVNQGPMEMASVFLSNLSDGTTVPT 1985
||||||||:||||.|||.||:|:|||||:|||||||.:||||||||:|:|.||||.: .|.....
Mouse 1994 PIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEI-PGDPKLF 2057
Fly 1986 KHQNKLRLCFREFSKRCADALKKNRNLILSDQKDYQRELERNNDRFIERLTPFI 2039
:|.|||||||::|:|||.|||:||::||..|||:||||||||..|..|.|.|.|
Mouse 2058 RHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLI 2111
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