Protein Alignment Zir and spg

DIOPT Version :9

• Sequence 1: NP_608489.2
• Gene: Zir / 33165
• FlyBaseID: FBgn0031216
• Length: 2064
• Species: Drosophila melanogaster
• Sequence 2: NP_733258.4
• Gene: spg / 43404
• FlyBaseID: FBgn0264324
• Length: 2187
• Species: Drosophila melanogaster
• Alignment Length: 2059
• Identity: 398/2059 - (19%)
• Similarity: 667/2059 - (32%)
• Gaps: 724/2059 - (35%)

  Fly    83 PRKIRTVD-------HVVPNENLSDLPHHVQECVNCYTRPWKVVEYAQRHLSSSCYIRERIDRGT 140
            |||.|.|.       |:   ::||.:...|.||.. ..|.|           |..:.|..:||
  Fly    47 PRKSRAVGLFPKTYIHI---KDLSKIDPVVAECTQ-VLREW-----------SEIWKRLYVDR-- 94

  Fly   141 ISPSAYQQEFEIDKDFSSFEEAFAYKSE--SCTPSSRQSIASLASVSSCTDTLTPRGSWASFDLR 203
               .||:.:......||..|.    :.|  |.|.:..|::.....|.|..|       |.:..|.
  Fly    95 ---EAYKFQTLRKVMFSILES----RRELLSATMTQDQTLELQMVVVSKID-------WGNRKLG 145

  Fly   204 RSVNDPLIPNLLDNVPPE------------------HIDQSNEARRQQDRQMALFSLYPESEAEE 250
                       ||.||.|                  |:..::.|:              .|.:..
  Fly   146 -----------LDLVPREGPLAVDPHGIGIVKLYNVHVSSADNAK--------------ASSSRG 185

  Fly   251 NIERRLLAEIPVEHM-------GHRIQVNCLQLRLELEVEPIFASMAIYDAKERQKISENFYFDM 308
            .:.|:...:|...|:       ||||..:        :.|..|   .:||....:.:||.|...:
  Fly   186 TLRRKTQRKILTHHLYFCMRDFGHRIGGD--------DAEVYF---FLYDGSHMRPLSERFLVKI 239

  Fly   309 NADSLKRMLSS-HVQC--------ADISTQSHSAIFEISYPSNDLFLVIRLEKVLQGDINNSVEP 364
            :.|.....:.. |..|        ||::.:.|.           :.:|:|:.|::|.|....:|
  Fly   240 SKDGFSNYIERLHSNCTVFTDLGAADLNEELHL-----------VAVVMRVGKIIQSDSIKKIE- 292

  Fly   365 YLKEDKDKYREKVKSNAVDYCERLGKYRMPFAWTGIYLTNVFNGDNFESKDAGAAERDSFGNACG 429
                         ||..:.:..   .:|.||. .|:.
  Fly   293 -------------KSGTLGHGP---TFRRPFG-VGVL---------------------------- 312

  Fly   430 SSLGTAPSSNSLDRKSSTSSFDQLRRKANDMSGTLTRRGSLERKEKHRSWSPDDFANVVENFRPI 494
             |||            ..:.||                .|||:....|.:          ||:
  Fly   313 -SLG------------DIAHFD----------------SSLEQSSDEREY----------NFK-- 336

  Fly   495 TITVPSFFKQEADKMKDEDLYKILPEL--KRPSSVMKKYKCIPGSIKLEISPCVEEAKNALTPEL 557
                 .|..:|.|       :.:||||  |:.|......:...|:..:.:|..:.........:.
  Fly   337 -----LFQCEEKD-------FHLLPELIIKKSSGKYSPIQASQGTQGIVVSLKLLHGGLGQARQE 389

  Fly   558 APINPQSADNVRPVKEILEFPQSAIYNPHYSYRNLLFVSPKELNFSSRAG--SARNIAVRVQLM- 619
            .|:..|.:...|.    :.||.  :..|. ..||.||::.:...| .|.|  :.:||.|.|.::
  Fly   390 QPMLFQGSTITRK----MGFPD--VIMPG-DVRNDLFLNLERGEF-ERGGKNTGKNILVTVVVLD 446

  Fly   620 -AGETPKDAVNAIYGKSSCPKFSTEAFTAVNYHNKCPSFYDEIKIALPASIKQHHHLLFTIYHVS 683
             ||....|.:....|..|.|::.    :.:.||...||:.:.:::::|.......|:.|...|.|
  Fly   447 VAGNVLTDCLWGASGMESQPQYR----SMILYHQNAPSWNEMLRLSVPIDKFSTAHVRFEFRHCS 507

  Fly   684 CQKKPQDLQPSVETPIGYTWLPLLEDGKLKFGEFNLPVMVESPPENYSFIPPNVHLPGIKWLDNH 748
            .:.|.:                                     |:.::|
  Fly   508 TRDKTE-------------------------------------PKLFAF---------------- 519

  Fly   749 RAVFSINVEAVTAIHTLDSFLDRFFLICEYLDTRNIPSHIGENNIETELKKCLLDIEYANREPLV 813
                              ||       ...:||..  :.:|:...|..:.||        .:|
  Fly   520 ------------------SF-------ARLMDTGG--ATLGDGLHELYVYKC--------EDP-- 547

  Fly   814 RHLPLVLDKLIELLVVTHKVGGQAMSLGSTVFEVLCLVSSLLSILNDDQYDQYGRQSLLSTYVHF 878
                                                   :.|.:.|               |:..
  Fly   548 ---------------------------------------AKLQVAN---------------YLRL 558

  Fly   879 QCKIPHPFQSK-----------------QRLTCSRSTTEDLQLS-----ESY--TIYDNVLASGR 919
            ||: |...|:|                 :.|.||...|::..|.     .:|  ||.|::....|
  Fly   559 QCR-PRDAQAKMDCGGCFSRSSKEVFVLRSLLCSTKLTQNADLLSLLQWRTYPETIQDSLTGVLR 622

  Fly   920 SLDRKEL------SIDVLHSMAARDVQVRLLHEELALHWVVASGKAADLAMSNSWFLFELIVKSM 978
             |:.:||      .:|.|.:|.:.:......|..|..|.:|:   ...|..||.:..|..::...
  Fly   623 -LNDEELVKFLQDVLDALFAMFSNEEGNSTQHSGLVFHVLVS---IFSLLQSNKFQHFRPVMNEY 683

  Fly   979 IEHLHCSNTLNGPRKHRFPHQFNDDLSTLVHLVTTKVVGYHSNEPKLAQSLNASLGFFIFDILSI 1043
            ||: |.:..|          .:...::::.|:........|   |...|....||. :||.:| |
  Fly   684 IEN-HFAAAL----------VYKGLITSVEHMAVFMTKAEH---PDPFQKCFGSLE-YIFKLL-I 732

  Fly  1044 MDRGFVFGLIKTYTKVLISKNASIPDLMNYKIDFLRIVCSHEHFVALN----LPFGTSYTMVTAP 1104
            ..|       |.:.:....:         |:..|.|.:  |..|.|||    :|   ||.::.
  Fly   733 QSR-------KLFARATGGQ---------YEDSFKRDL--HSLFTALNGMLAVP---SYDVII-- 774

  Fly  1105 CSPTPSTTSSNSQTSCGSLERALHADLSQEFLQQHFLVGLVLSDLAAVMEVPNPQL--------- 1160
              ||                        ||.|...  .|:||..|...:  |.|:|
  Fly   775 --PT------------------------QEALLNS--TGVVLEQLKDTL--PAPELGMLARNMLD 809

  Fly  1161 ---HGKAIRCIR-NLMTSHDL--DARYSETDARARVAALYIPLLSIVMDCIPQLHQHGLEQDRL- 1218
               .|..||.|: .|....||  ...:.|.|:|..|       ||:.  | ..|..|...:|.|
  Fly   810 AIPRGAPIRLIQAKLHAVKDLVSGELFHEDDSRTVV-------LSVA--C-KHLRMHLSRRDELR 864

  Fly  1219 -------QQIGQLEDYQGPHQTITASTINPEVAFAISG-----SRPYSYLNEQVKNKLPLSSENT 1271
                   :.:.||.|.|...:....:|:..::......     .|..|.:.|.....||
  Fly   865 LCAEILSEILSQLYDLQKEQREKVTNTLQHDLDSLCKNILGILIRTISIIMEGSNAVLP------ 923

  Fly  1272 RHLLVCFLWVLKNLERNVLYRWLMDLSPHRVHQMLQGVNVCLKTFEYTGQKNVATLKRTNTQSFR 1336
             .|:.|.|.:|:.|:.....|:..:|||::..:.|:         |:. .|::...:...||.:.
  Fly   924 -QLVSCLLGLLQLLDETHYKRYWDELSPNKDPRDLK---------EFL-SKSLLVYEELLTQDWH 977

  Fly  1337 KTGSTDVKEKLEECIRGTNSARYDLINRRKDRNSTEKFRWRKDQMPYRSQYADAVGKSEHELELS 1401
            ...:..:..||         |..|::     |.|.|:|   ...:.||.....|.   :.:|..|
  Fly   978 VFPNDWLVMKL---------AANDVL-----RMSLEEF---AKPLVYRFLGPQAF---DSQLWWS 1022

  Fly  1402 HFIEGSLATEVALVLLDTLEI----------IVHAAANLYHNLLGTVLKVLLHSLSRNQSVLALQ 1456
            :|   |||  ||.:...:|::          |:|:..:         ::||:     ...:|::.
  Fly  1023 YF---SLA--VAFLTQPSLQLEQYREPKRLKILHSHGD---------MRVLM-----GFQILSMW 1068

  Fly  1457 NLFASQRALIFKFPNLLFDDETDICADLCLILLKHCGSLL-------PGIRSQAAASLYLLMRQN 1514
            :....|:  :...|:::                   |..|       |.:|....:..|.:|:..
  Fly  1069 SQLGEQK--LHFIPSMV-------------------GPFLEVTLVPEPALRKATLSVFYDMMQCE 1112

  Fly  1515 FEIGNNFARVKMQVTMSLSSLVGTSSVFSEQSLRRALKTVLVYAESDSDLQDTSFPEQVQDLLFN 1579
            .....:|..|:.::...|..|:..:.  .:...|....|:|:   ....:::.::.|.....:.:
  Fly  1113 QAARGSFRLVESELIDKLDLLISENK--GDDEYRELFSTILL---EKVQVENPNWKEAGIAFIAS 1172

  Fly  1580 LHMILSDTVKMKEYQEDPEMLLDLMNRIAKGYQNNPDLRLTWLENMAKKHRERANHTEAAMCYV- 1643
            :..:|             |.|||..: :.:| :.|.|.|:|...|:...::...|..|..:.|:
  Fly  1173 VTRLL-------------ERLLDYRS-VMQG-EENRDKRMTCTVNLLNFYKNEINRKEMYLRYIY 1222

  Fly  1644 --HAASLVSE-----------YLSML----ESQKHLPV---GAVSFQRISPNTLMESAVSDDVLS 1688
              |...|.:|           |.|||    |:|...|.   |...:||       :..:..::|.
  Fly  1223 KLHNLHLQAENYTEAGFTLKLYASMLSWDRETQSFAPFDNSGQPEWQR-------KERLYHEILK 1280

  Fly  1689 PGEDGICLGNHFTETGLKALLEEASNSFQVAGMYEAMNEVYKILIPICEANRDFQKLSKVHGKLQ 1753
            ..:.|.|     .|.|:....|       :|.:||.             ...|:.|||::  .:|
  Fly  1281 YFDKGKC-----WEKGIPLCKE-------LAHLYET-------------RRFDYNKLSEI--LIQ 1318

  Fly  1754 EA---FNRISQLQGKRVFGTYFRVGFYG-GKFGDLDQQEFIYKEPTLTKLPEIFSRLQNFYTERF 1814
            ||   .|.::||   |....|||||||| |....:..::|:|:.....::.....|||..:
  Fly  1319 EAKFFQNILTQL---RPEPEYFRVGFYGMGLPLFVRNKQFVYRGLEYERIGAFTQRLQTEF---- 1376

  Fly  1815 GPDSVHIIKDSNTVDINSLDPDKAYIQITYVEPYFETYEMRHR--------ETYFERNFNIKRFI 1871
              .|..|:.:::..|...|:....||||:.|.|..:...::..        ..::|.| ::.|||
  Fly  1377 --PSAQILGNNSPPDNAILNAPDQYIQISNVRPVGDAQALKTAMVPVPEKIARFYEVN-DVTRFI 1438

  Fly  1872 YATPFTKNG-KAHGELNEQCKRKTILTTANHFPYVKTRIMVISRQQIVLEPIEVAIEDIQKKTLE 1935
            |..|..|.. ....|.......:|||..|:..|.:.....|..:....|.|:|.|.|.|.....|
  Fly  1439 YDRPMYKGTVDKDNEFKSLWIERTILEIASPLPGILRWYEVKQKTMQELTPVEYACEIISNAGKE 1503

  Fly  1936 LAAATNQEPADPK----ILQMVLQGCIGTTVNQGPMEMASVFLS 1975
            |:....|...|||    ...|.|||.|...|..|..:....|.|
  Fly  1504 LSELIVQYKRDPKRNINPFSMRLQGTIDANVMGGISKYQEAFFS 1547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zir	NP_608489.2	DUF3398	59..151	CDD:288711	19/74 (26%)
		C2_Dock-C	589..769	CDD:176078	30/183 (16%)
		DHR-2	1549..2037	CDD:284365	110/465 (24%)
spg	NP_733258.4	SH3_DOCK_AB	9..64	CDD:212805	6/19 (32%)
		DOCK_N	67..406	CDD:292790	89/516 (17%)
		C2_Dock-B	414..600	CDD:176077	50/335 (15%)
		DHR2_DOCK	1215..1610	CDD:297424	95/377 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1997
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810