DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11374 and Lgals3

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_114020.1	Gene:	Lgals3 / 83781	RGDID:	69356	Length:	262	Species:	Rattus norvegicus

Alignment Length:	134	Identity:	36/134 - (26%)
Similarity:	57/134 - (42%)	Gaps:	20/134 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PRPG-----LCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQN---YITRNSRL 97
            |.||     :.....|.:........::|  |:|:      |:......|..:|   .|..|::.
  Rat   133 PLPGGVMPRMLITIIGTVKPNANSITLNF--KKGN------DIAFHFNPRFNENNRRVIVCNTKQ 189

  Fly    98 KGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVS 162
            ...||.||..|  .|....||.|.:|:|:..:.|.::||..|..:|.|||  :.|..:..||.:.
  Rat   190 DNNWGREERQS--AFPFESGKPFKIQVLVEADHFKVAVNDVHLLQYNHRM--KNLREISQLGIIG 250

  Fly   163 DIVI 166
            ||.:
  Rat   251 DITL 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	34/128 (27%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752
Lgals3	NP_114020.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..102
		Bindin	18..>116	CDD:251078
		9 X 9 AA tandem repeats of Y-P-G-X(3)-P-[GS]-[AG]	35..112
		GLECT	129..256	CDD:238025	36/134 (27%)
		Beta-galactoside binding. /evidence=ECO:0000250	193..199		4/5 (80%)
		Nuclear export signal. /evidence=ECO:0000250	238..253		4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7884
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820