DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and lgals4

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_005173755.1	Gene:	lgals4 / 567193	ZFINID:	ZDB-GENE-141222-13	Length:	2601	Species:	Danio rerio

Alignment Length:	356	Identity:	88/356 - (24%)
Similarity:	150/356 - (42%)	Gaps:	42/356 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RSEAHRRKHFKVIQCPR------PGLCFVFHGMILMACEHFVIDFLTKQGSEICEEC---DVLLQ 81
            ||..|....|.|....|      .|......|.:....:.||::..       |.|.   |:..|
Zfish    10 RSSCHTTSGFSVPYVSRIHGGLKAGKGVFIQGAVPAGSDGFVVNLK-------CGESDGDDIAFQ 67

  Fly    82 IGSRLPQNYITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHR 146
            :..:...|:...|||..|.||.||.   |.|.|..|.||.:.|.:..|.:.:.::|.....:.||
Zfish    68 MKPQFISNFTAVNSRQNGSWGKEEK---LDFPLKPGSSFDLNIAVNSEGYQVFLSGQEVGCFQHR 129

  Fly   147 MPYRWLEAVDVLGDVS--DIVIDTYYVSEYPIR----LTHSLPRPIPHSNKLPRDGENVETEWMV 205
            :....:..:.|.|.||  :::....:.....||    :.|| ...:...:...|:|....||...
Zfish   130 ISLERVNTLAVAGGVSLTNVMFTEGWSGSSSIRGGRGMHHS-HHGVFRGHSSMREGTWSFTETKH 193

  Fly   206 LSSLAKMSSKKFLYQP--SLPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWP 268
            ..|...::::..|..|  :..||:.|.:  ...|.||.:|.::|.|.....||::.|:.|  |..
Zfish   194 HPSTTHLTTELSLSNPVQNPKLPYVGPI--SGGLREGMALYVKGVVPNNADRFALNFKTG--ISD 254

  Fly   269 QPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYE 333
            :..|:|:|:|...:.         :|..::.||.| ....|..:...:.|..|.::.|...:.|:
Zfish   255 KDDVAFHFNPRMEQK---------VTMNSFQNGAW-GTEESVSDNPFKKGQDFEMLTAITSAGYQ 309

  Fly   334 LFVNNRSLFHFKYQMRPECVDIVNIRGDIKL 364
            ::||.:.|:.||:.:..|.|.::||.||:.|
Zfish   310 VYVNGKELYTFKHHIPLEKVAVLNIGGDVTL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	32/133 (24%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	38/139 (27%)
lgals4	XP_005173755.1	Gal-bind_lectin	22..149	CDD:278752	33/136 (24%)
		GLECT	216..340	CDD:238025	37/137 (27%)
		Gal-bind_lectin	389..518	CDD:278752
		Gal-bind_lectin	528..655	CDD:278752
		Gal-bind_lectin	703..830	CDD:278752
		Gal-bind_lectin	840..967	CDD:278752
		Gal-bind_lectin	1013..1142	CDD:278752
		Gal-bind_lectin	1152..1279	CDD:278752
		Gal-bind_lectin	1325..1454	CDD:278752
		Gal-bind_lectin	1464..1591	CDD:278752
		Gal-bind_lectin	1642..1766	CDD:278752
		Gal-bind_lectin	1776..1903	CDD:278752
		Gal-bind_lectin	1949..2073	CDD:278752
		Gal-bind_lectin	2122..2246	CDD:278752
		GLECT	2295..2422	CDD:238025
		Gal-bind_lectin	2468..2593	CDD:278752
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020