DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11374 and Lgals12

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001343503.1	Gene:	Lgals12 / 56072	MGIID:	1929094	Length:	314	Species:	Mus musculus

Alignment Length:	190	Identity:	48/190 - (25%)
Similarity:	85/190 - (44%)	Gaps:	27/190 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 FLYQPSL--PLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPC 279
            |:.||.:  |:..||..:... |..|..:.::|.|.|..:||.:.||.|..:.|||.|:|.|||.
Mouse    14 FILQPPVFHPVIPYGTTIFGG-LYAGKMVTLQGVVPLHARRFQVDFQCGCCLHPQPDVAFRFSPR 77

  Fly   280 FLRSR-HDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFH 343
            |...: |       :....:..|.|.. .:.....:|:.|.:|:|:....:...::.||.:...|
Mouse    78 FYTVKPH-------VICNTHQGGLWQK-EIRWPGVALQRGDSFLILFLFENEEVKVSVNGQHFLH 134

  Fly   344 FKYQMRPECVDIVNIRGDIKLWEVA-------IQGNTTYK--------KPKVRSAMERAI 388
            ::|::....||.::|.|||.:..|.       ::|:..|.        .|::.....||:
Mouse   135 YRYRLPLSRVDTLDISGDILVKAVGFLNINPFVEGSREYPVGYPFLLYSPRLEVPCSRAL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	39/150 (26%)
Lgals12	NP_001343503.1	Gal-bind_lectin	26..158	CDD:366037	38/140 (27%)
Lgals12	NP_001343503.1	Gal-bind_lectin	195..313	CDD:214904	48/190 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840837
Domainoid	1	1.000	54	1.000	Domainoid score	I11154
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S7663
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.700