Protein Alignment CG11374 and LGALS8

DIOPT Version :9

• Sequence 1: NP_608488.3
• Gene: CG11374 / 33163
• FlyBaseID: FBgn0031214
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_006490.3
• Gene: LGALS8 / 3964
• HGNCID: 6569
• Length: 359
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 81/360 - (22%)
• Similarity: 140/360 - (38%)
• Gaps: 67/360 - (18%)

  Fly    43 PGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQ-NYITRNSRLKGKWGPEEN 106
            ||...|..|.:....:.|.:|.  :.||.:....||......|..: ..|..|:.:..|||.||
Human    29 PGTLIVIRGHVPSDADRFQVDL--QNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE- 90

  Fly   107 SSYLTFQ--LNRGKSFWMQILLTEECFFISVNGYHFAKYFHRM-PYRWLEAVDVLGDVSDIVI-- 166
               :|:.  ..|.|||.:.|::.::.|.::|||.|...|.||: |    |.:|.||....:.|
Human    91 ---ITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGP----EKIDTLGIYGKVNIHS 148

  Fly   167 -------DTYYVSEYPIRLTHSLPRPIPHSN--KLP--RDGENVETEWMVLSSLAKMS----SKK 216
                   |........:.||......:|.|.  :||  |.|:        :|.:|..:    ||.
Human   149 IGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLPSNRGGD--------ISKIAPRTVYTKSKD 205

  Fly   217 FLYQPSLP-------------LPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWP 268
            .....:|.             |||..:|  ...:..|.::.::|.|....:.|::....|:
Human   206 STVNHTLTCTKIPPMNYVSKRLPFAARL--NTPMGPGRTVVVKGEVNANAKSFNVDLLAGK---- 264

  Fly   269 QPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYE 333
            ...::.:.:|        ::......|.::|...|.....:..:....||..|.::|.|....::
Human   265 SKDIALHLNP--------RLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFK 321

  Fly   334 LFVNNRSLFHFKYQMRP-ECVDIVNIRGDIKLWEV 367
            :.||......:|::.:. ..:|.:.|.|||.|.||
Human   322 VAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEV 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	37/122 (30%)
		Gal-bind_lectin	226..369	CDD:278752	28/143 (20%)
LGALS8	NP_006490.3	Gal-bind_lectin	18..151	CDD:278752	38/131 (29%)
		Gal-bind_lectin	236..356	CDD:214904	23/131 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8848
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4712
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm8457
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.970