Protein Alignment CG11374 and LGALS4

DIOPT Version :10

• Sequence 1: NP_608488.3
• Gene: CG11374 / 33163
• FlyBaseID: FBgn0031214
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_006140.1
• Gene: LGALS4 / 3960
• HGNCID: 6565
• Length: 323
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 87/340 - (25%)
• Similarity: 152/340 - (44%)
• Gaps: 49/340 - (14%)

  Fly    41 PRPGLCFVFHGMIL----MACEH---FVIDFLTKQ--GSEICEECDVLLQIGSRLP-QNYITRNS 95
            |.||...|  ||.:    :|.||   |.::|:..|  ||      ||......|.. .:.:..|:
Human    22 PIPGGLNV--GMSVYIQGVASEHMKRFFVNFVVGQDPGS------DVAFHFNPRFDGWDKVVFNT 78

  Fly    96 RLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGD 160
            ...||||.||....:.|:  :|.:|.:..::..|.:.:.|||..|.:|.||:|.:.:..:.|.||
Human    79 LQGGKWGSEERKRSMPFK--KGAAFELVFIVLAEHYKVVVNGNPFYEYGHRLPLQMVTHLQVDGD 141

  Fly   161 VSDIVIDTYYVSEYPIRLTHSLPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPSLPL 225
            :....|:  ::...|:|     |:..|.....|..|...:.    |:||..|.... .:.|  |:
Human   142 LQLQSIN--FIGGQPLR-----PQGPPMMPPYPGPGHCHQQ----LNSLPTMEGPP-TFNP--PV 192

  Fly   226 PFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGT 290
            |::|:|  :..|....::.|:|.|....:.|:|.|:.|.    ...::.:.:|        ::|.
Human   193 PYFGRL--QGGLTARRTIIIKGYVPPTGKSFAINFKVGS----SGDIALHINP--------RMGN 243

  Fly   291 AIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMRP-ECVD 354
            ..:.|.:.|||.|.:......:....||..|.:.|.|....::::.|.:.||.|.:::.. :.||
Human   244 GTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRVD 308

  Fly   355 IVNIRGDIKLWEVAI 369
            .:.|:||:.|..|.|
Human   309 TLEIQGDVTLSYVQI 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	42..162	CDD:459768	38/129 (29%)
		Gal-bind_lectin	237..367	CDD:459768	30/130 (23%)
LGALS4	NP_006140.1	GLECT	18..147	CDD:238025	39/134 (29%)
		Gal-bind_lectin	199..322	CDD:214904	30/134 (22%)