DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and lgals3b

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_999858.2	Gene:	lgals3b / 325599	ZFINID:	ZDB-GENE-030131-4324	Length:	228	Species:	Danio rerio

Alignment Length:	130	Identity:	32/130 - (24%)
Similarity:	58/130 - (44%)	Gaps:	14/130 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQN---YITRNSRLKGKWGPEEN 106
            :....:|.:....:.|.::.  ::|:      |:...|..|..:.   .|.|||.:...||.||.
Zfish   106 MLITINGEVKPNAKQFTVNL--RRGN------DIAFHINPRFSEGGKPVIVRNSMIGNNWGREER 162

  Fly   107 SSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYV 171
             ...:|....||.|.|:||:|:..:.::||..|..::.||:  ..|..:..|...:|:.:.|..|
Zfish   163 -ELPSFPFVPGKPFEMKILITDTEYKVAVNKSHLLEFKHRV--FELNQITGLSIYNDVTLSTVNV 224

Fly 172 171
Zfish 225 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	29/119 (24%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752
lgals3b	NP_999858.2	Gal-bind_lectin	99..223	CDD:214904	31/127 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9258
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820