DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and LGALSL

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_054900.2	Gene:	LGALSL / 29094	HGNCID:	25012	Length:	172	Species:	Homo sapiens

Alignment Length:	153	Identity:	33/153 - (21%)
Similarity:	63/153 - (41%)	Gaps:	21/153 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 LYQPSLPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLR 282
            :|.|.|.:||.|.:  :..:..|..:.:.|.|.|.|:.|:|:...|....|...|:....
Human    31 VYFPRLIVPFCGHI--KGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELK----- 88

  Fly   283 SRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLR-----PGGAFVIVIACRDSYYELFVNNRSLF 342
                    |:.|.|..|....::.......:::.     |...|.:.|.|....:.:||:...||
Human    89 --------AVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLF 145

  Fly   343 HFKYQMRP-ECVDIVNIRGDIKL 364
            .|.::::. ..:|.:.|.||:::
Human   146 DFYHRIQTLSAIDTIKINGDLQI 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	30/145 (21%)
LGALSL	NP_054900.2	Gal-bind_lectin	46..170	CDD:214904	27/136 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8848
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820