DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11374 and LGALS9B

DIOPT Version :9

Sequence 1:NP_608488.3 Gene:CG11374 / 33163 FlyBaseID:FBgn0031214 Length:401 Species:Drosophila melanogaster
Sequence 2:NP_001354221.1 Gene:LGALS9B / 284194 HGNCID:24842 Length:356 Species:Homo sapiens


Alignment Length:351 Identity:85/351 - (24%)
Similarity:145/351 - (41%) Gaps:51/351 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 GLCFVFHGMILMAC-EHFVIDFLTK-QGSEICEECDVLLQIGSRLPQNYITRNSRLKGKWGPEEN 106
            |.....:|.:|.:. ..|.:||.|. .|::|....:...:.|     .|:..|:|.||:|||||.
Human    28 GFQITVNGAVLSSSGTRFAVDFQTGFSGNDIAFHFNPRFEDG-----GYVVCNTRQKGRWGPEER 87

  Fly   107 SSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYV 171
            ..::.||  :|..|.:..|:....|.:.|||..|.:||||:|:..::.:.|.|.|....|.....
Human    88 KMHMPFQ--KGMPFDLCFLVQSSDFKVMVNGSLFVQYFHRVPFHRVDTISVNGSVQLSYISFQNP 150

  Fly   172 SEYPIRLTHSL----------PRPIPHSNKLP--RDGENVETEWMVLSSLAKMSSKKF------- 217
            ...|::...|.          |||.....|.|  |..........|:.::...|.:.|       
Human   151 RTVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPSVRPANPAPITQTVIHTVQSASGQMFSQTPAIP 215

  Fly   218 --LY-QPSLPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPC 279
              :| .|:.|:||...:  ...|....|:.:.|.|....|||.|....|..|      :|:.:|.
Human   216 PMMYPHPAYPMPFITTI--PGGLYPSKSIILSGTVLPSAQRFHINLCSGSHI------AFHMNPR 272

  Fly   280 FLRSRHDKIGTAIITRRAYLNGDW--VNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLF 342
            |..:        .:.|...:|..|  ...::.|....:| |.:|.:.|.|.....::.|:.:.:|
Human   273 FDEN--------AVVRNTQINNSWGSEERSLPRKMPFVR-GQSFSVWILCEAHCLKVAVDGQHVF 328

  Fly   343 HFKYQMRP-ECVDIVNIRGDIKLWEV 367
            .:.:::|. ..::.:.:.|||:|..|
Human   329 EYYHRLRNLPTINKLEVGGDIQLTHV 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11374NP_608488.3 Gal-bind_lectin 37..162 CDD:278752 37/119 (31%)
Gal-bind_lectin 226..369 CDD:278752 32/145 (22%)
LGALS9BNP_001354221.1 GLECT 16..146 CDD:238025 38/124 (31%)
Beta-galactoside binding 1. /evidence=ECO:0000250 82..88 5/5 (100%)
DNA_pol3_gamma3 <150..>227 CDD:331207 14/76 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 170..190 6/19 (32%)
Gal-bind_lectin 233..355 CDD:214904 30/137 (22%)
Beta-galactoside binding 2. /evidence=ECO:0000250 288..294 1/5 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165150755
Domainoid 1 1.000 80 1.000 Domainoid score I8601
eggNOG 1 0.900 - - E1_KOG3587
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 125 1.000 Inparanoid score I4712
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D357844at33208
OrthoFinder 1 1.000 - - FOG0000178
OrthoInspector 1 1.000 - - mtm8457
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X133
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
109.800

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