DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and Lgals4

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_008757335.1	Gene:	Lgals4 / 25474	RGDID:	3003	Length:	349	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	82/360 - (22%)
Similarity:	143/360 - (39%)	Gaps:	74/360 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLP-QNYITRNSRLKGKWGPEENS 107
            |:.....|:.......|.::|...|.    |..|:......|.. .:.:..|:...|:||.||..
  Rat    30 GMSIYIQGIAKDNMRRFHVNFAVGQD----EGADIAFHFNPRFDGWDKVVFNTMQSGQWGKEEKK 90

  Fly   108 SYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVS----DIVIDT 168
            ..:.||  :|..|.:..::..|.:.:.|||..|.:|.||:|.:.:..:.|.||:.    :.:...
  Rat    91 KSMPFQ--KGHHFELVFMVMSEHYKVVVNGTPFYEYGHRLPLQMVTHLQVDGDLELQSINFLGGQ 153

  Fly   169 YYVSEYPIRLTHSLPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPSLPLPFYGKLLK 233
            ...|:||..:|      ||   ..|..|.|...    ::||..|:... ::.|  |:|:.|.|
  Rat   154 PAASQYPGTMT------IP---AYPSAGYNPPQ----MNSLPVMAGPP-IFNP--PVPYVGTL-- 200

  Fly   234 ENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAY 298
            :..|....::.|:|.|....:...|.|:.|.    ...::|:.:|        :||..:: |.:|
  Rat   201 QGGLTARRTIIIKGYVLPTAKNLIINFKVGS----TGDIAFHMNP--------RIGDCVV-RNSY 252

  Fly   299 LNGDWVNCTVSRLNTSLRPGGA----------------------------FVIVIACRDSYYELF 335
            :||.|.:   ........|.||                            ..:.|.|....:::|
  Rat   253 MNGSWGS---EERKIPYNPFGAGQFFDVSLGVLFSVPTNPSLAGPHLSFPLQLSIRCGTDRFKVF 314

  Fly   336 VNNRSLFHFKYQMRP-ECVDIVNIRGDIKLWEVAI 369
            .|.:.||.|.::.:. :.||::.|:|||.|..|.|
  Rat   315 ANGQHLFDFSHRFQAFQRVDMLEIKGDITLSYVQI 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	30/118 (25%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	37/171 (22%)
Lgals4	XP_008757335.1	Gal-bind_lectin	24..148	CDD:214904	30/123 (24%)
Lgals4	XP_008757335.1	Gal-bind_lectin	201..348	CDD:214904	33/162 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7884
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm8932
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970