DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and Lgals3

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001139425.1	Gene:	Lgals3 / 16854	MGIID:	96778	Length:	264	Species:	Mus musculus

Alignment Length:	134	Identity:	38/134 - (28%)
Similarity:	57/134 - (42%)	Gaps:	20/134 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PRPG-----LCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQN---YITRNSRL 97
            |.||     :.....|.:.......|:||  ::|:      ||......|..:|   .|..|::.
Mouse   135 PLPGGVMPRMLITIMGTVKPNANRIVLDF--RRGN------DVAFHFNPRFNENNRRVIVCNTKQ 191

  Fly    98 KGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVS 162
            ...||.||..|  .|....||.|.:|:|:..:.|.::||..|..:|.|||  :.|..:..||...
Mouse   192 DNNWGKEERQS--AFPFESGKPFKIQVLVEADHFKVAVNDAHLLQYNHRM--KNLREISQLGISG 252

  Fly   163 DIVI 166
            ||.:
Mouse   253 DITL 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	36/128 (28%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752
Lgals3	NP_001139425.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..105
		Bindin	18..>110	CDD:251078
		9 X 9 AA tandem repeats of Y-P-G-X(3)-P-[GS]-A	35..114
		Gal-bind_lectin	137..258	CDD:214904	37/132 (28%)
		Beta-galactoside binding. /evidence=ECO:0000250	195..201		4/5 (80%)
		Nuclear export signal	240..255		4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7822
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820