DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and CLC

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001819.2	Gene:	CLC / 1178	HGNCID:	2014	Length:	142	Species:	Homo sapiens

Alignment Length:	158	Identity:	41/158 - (25%)
Similarity:	70/158 - (44%)	Gaps:	23/158 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 LPLPFYGKLLKENFLIEGSSLRIEGR---VRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSR 284
            ||:|:    .:...|..||::.|:||   ..|......:.|.  .|:..:..:.|:|..||.|
Human     4 LPVPY----TEAASLSTGSTVTIKGRPLACFLNEPYLQVDFH--TEMKEESDIVFHFQVCFGR-- 60

  Fly   285 HDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMR 349
                 ..::..|.|  |.|.....|: |...:.|..|.:.|:.....|::.||.:|.:.|.::::
Human    61 -----RVVMNSREY--GAWKQQVESK-NMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIK 117

  Fly   350 PECVDIVNIRGDIKLWEVAIQGNTTYKK 377
            ||.|.:|.:..||.|.:.    |.:|.|
Human   118 PEAVKMVQVWRDISLTKF----NVSYLK 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	36/145 (25%)
CLC	NP_001819.2	Gal-bind_lectin	5..137	CDD:278752	37/151 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150752
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750