DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11374 and lgals9

DIOPT Version :9

Sequence 1:	NP_608488.3	Gene:	CG11374 / 33163	FlyBaseID:	FBgn0031214	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_012808599.1	Gene:	lgals9 / 100145704	XenbaseID:	XB-GENE-5813327	Length:	446	Species:	Xenopus tropicalis

Alignment Length:	343	Identity:	75/343 - (21%)
Similarity:	145/343 - (42%)	Gaps:	70/343 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQNYITRNSRLKGKWGPEENSS 108
            |......|::...|:.|.::|       ||...||......|..::.|..|::|..:||.||.:.
Frog    25 GKTLTIEGLVHNDCKRFAVNF-------ICFNNDVAFHFNPRFDKDNIACNTKLSNQWGLEERTD 82

  Fly   109 YLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSE 173
            ::.|..|  ::|.:.|.:....|.:||||.|..:|.||:.|:.::::.:.|   ||.::....|:
Frog    83 HMLFGHN--EAFEITITVLRSAFKVSVNGDHILEYRHRISYQGIQSLQLNG---DITLNKVTFSD 142

  Fly   174 YPIRLTHSLPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPSLPLPFYGKLLKENFLI 238
            .|                               |.::....|:....|:..:||...:  ...:.
Frog   143 PP-------------------------------SQISTAPEKQLSVAPNYSIPFQSAI--PGRIS 174

  Fly   239 EGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDW 303
            :|.::.|||.|.....||::.|     :......:|:|:|     |.|:..|.:...:  |:..|
Frog   175 DGKTVTIEGLVHSDCNRFTVNF-----LCFNNDTAFHFNP-----RFDEDNTIVCNTK--LDNKW 227

  Fly   304 VNCTVSRLNTSLRP---GGAFVIVIACRDSYYELFVNNRSLFHFKYQMRPECVDIVNIRGDIKLW 365
              .:|.|  |.|.|   ..:|.|:|...:..:::.||.:.:..:.:::..:.:..|.::|||.|.
Frog   228 --GSVER--TQLMPFEKDDSFEIIIIIMEHVFQVSVNRKRILEYHHRVSYQGIQSVLVKGDITLL 288

  Fly   366 EVAIQGNTTYKKPKVRSA 383
                  |.|:.:|..:.:
Frog   289 ------NVTFSEPPAQES 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11374	NP_608488.3	Gal-bind_lectin	37..162	CDD:278752	32/117 (27%)
CG11374	NP_608488.3	Gal-bind_lectin	226..369	CDD:278752	33/145 (23%)
lgals9	XP_012808599.1	GLECT	13..139	CDD:238025	34/125 (27%)
		GLECT	164..291	CDD:238025	34/150 (23%)
		Gal-bind_lectin	322..442	CDD:214904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I7543
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4497
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm9348
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970