DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment galectin and Pex23

DIOPT Version :9

Sequence 1:NP_608487.1 Gene:galectin / 33162 FlyBaseID:FBgn0031213 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_730508.1 Gene:Pex23 / 40229 FlyBaseID:FBgn0052226 Length:1350 Species:Drosophila melanogaster


Alignment Length:489 Identity:93/489 - (19%)
Similarity:163/489 - (33%) Gaps:176/489 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 DLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADC 81
            |:.:.|.:....:.:.....:.::.:||      ..|:    |::|..:::.|.:|      .||
  Fly   614 DIVNKLQRRQEKLAKLQTVAKFEKAVEL------SSWV----KSADARYQRPGGEF------EDC 662

  Fly    82 VLNMD-----AFDDTTTELHKR--------FLQAEGTR---PFPSDCISGIEVVDGNEFKASFYE 130
            ::.::     :..||.:..:.|        .|..:|..   .||...|:.::...    :|....
  Fly   663 IIELEWVSSGSGTDTNSSENSRSGDSGTFTVLSPDGAATKIQFPLSDITCVQCCS----EAGAPR 723

  Fly   131 YADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDSRDVALHINPRLPQ-NYIVRN 194
            .|...|                    :|.|||....:....:::..|...|::....| |.:|..
  Fly   724 IAIHAP--------------------HLPVNCSPVKLQFSSDSEMEDWLSHLSSVCSQINTMVGK 768

  Fly   195 TKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKG 259
            .....||...|:.....|                                               
  Fly   769 PAGNAIWITSELGDVFVF----------------------------------------------- 786

  Fly   260 DVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSS 324
            |.:|::..:|           ||.:      :..:.::|.|..||                    
  Fly   787 DPANMKAHQT-----------SEPS------EGYVEKMDVSTCET-------------------- 814

  Fly   325 PKRNNSSNDLGLTLPYYGALPPNSLVDGRCLKIEG---------RVRLLPHSFYINLQQGQDIWP 380
                          |||..| .|.:..|..|:|.|         |..|..|| .:.:|..: :..
  Fly   815 --------------PYYNTL-YNGMPCGTELEISGCVYDDADQIRFDLQSHS-AVKVQPHR-VEK 862

  Fly   381 HPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFE 445
            |.|||.||||||::.::        ..|:.....|..|.|:: ...|.||.:|.|.|...:..:.
  Fly   863 HRVIALHLNPRFNERTT--------VLNSMKESEWLDEIRND-KMAFAPGATFSLKIRALQDHYL 918

  Fly   446 VYVNRQFMTDFKYKVSPEVVDTVYIQGDVKLWNV 479
            :.||....||:||::.||.|..:|:.|.:||:||
  Fly   919 IIVNNAVYTDYKYRIDPESVTRLYVSGRIKLFNV 952

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
galectinNP_608487.1 GLECT 143..262 CDD:238025 14/119 (12%)
Gal-bind_lectin 339..479 CDD:278752 47/148 (32%)
Pex23NP_730508.1 DysFN 64..125 CDD:214777
Hyd_WA 210..238 CDD:283993
Hyd_WA 257..282 CDD:283993
TECPR 280..320 CDD:214782
TECPR 338..371 CDD:214782
PH-like 639..759 CDD:302622 26/159 (16%)
Gal-bind_lectin 815..954 CDD:278752 49/150 (33%)
TECPR 966..1000 CDD:214782
DysFN 1021..1081 CDD:214777
DysFC 1092..>1113 CDD:128935
Hyd_WA 1165..1192 CDD:283993
Hyd_WA 1209..1237 CDD:283993
Hyd_WA 1308..1333 CDD:283993
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3587
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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