Protein Alignment galectin and LGALS9

DIOPT Version :10

• Sequence 1: NP_608487.1
• Gene: galectin / 33162
• FlyBaseID: FBgn0031213
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_033665.1
• Gene: LGALS9 / 3965
• HGNCID: 6570
• Length: 355
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 109/401 - (27%)
• Similarity: 168/401 - (41%)
• Gaps: 95/401 - (23%)

  Fly   124 FKASFYEY-ADAVPKYFNDQI-GKLSEGISFTVTGN-LSVNCERFSINLVYNNDSRDVALHINPR 185
            |..|...| :.|||  |:..| |.|.:|:..||.|. ||.:..||::|........|:|.|.|||
Human     3 FSGSQAPYLSPAVP--FSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPR 65

  Fly   186 LPQ-NYIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPY 249
            ... .|:|.||:....||.||..:.:||  .:|..|.:..||..:.:.:.|||..|..|.||:|:
Human    66 FEDGGYVVCNTRQNGSWGPEERKTHMPF--QKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPF 128

  Fly   250 RDVRILEVKGDVS----NVEMKRTLVLK-------------YPERLPQSEANNIELHIDDGINEI 297
            ..|..:.|.|.|.    :.:..||:.::             :|.| |:....
Human   129 HRVDTISVNGSVQLSYISFQNPRTVPVQPAFSTVPFSQPVCFPPR-PRGRRQ------------- 179

  Fly   298 DASVEETVKIPHEWCIISAPNTQS-----DSSPKRNNSSNDLGLTLPYYGALPP----------- 346
                    |.|..|....||.||:     .|:|.:..|:          .|:||
Human   180 --------KPPGVWPANPAPITQTVIHTVQSAPGQMFST----------PAIPPMMYPHPAYPMP 226

  Fly   347 ------NSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVV 405
                  ..|...:.:.:.|.|......|:|||..|..      |||||||||.:       .|||
Human   227 FITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNH------IAFHLNPRFDE-------NAVV 278

  Fly   406 CRNAWLNGAWAQEERS-EFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKV-SPEVVDTV 468
             ||..::.:|..|||| .....|..|:||.:.|:|.....:|.|:.|.:.::.::: :...::.:
Human   279 -RNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRL 342

  Fly   469 YIQGDVKLWNV 479
            .:.||::|.:|
Human   343 EVGGDIQLTHV 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025	43/121 (36%)
		Gal-bind_lectin	346..479	CDD:459768	40/151 (26%)
LGALS9	NP_033665.1	lectin domain	1..148		51/148 (34%)
		GLECT	16..146	CDD:238025	46/133 (35%)
		alternate exon	149..180		5/52 (10%)
		Peptidase_C62	<154..214	CDD:289173	14/91 (15%)
		link peptide	181..206		8/24 (33%)
		lectin domain	207..355		44/171 (26%)
		Gal-bind_lectin	233..354	CDD:214904	40/135 (30%)