Protein Alignment galectin and LGALS8

DIOPT Version :9

• Sequence 1: NP_608487.1
• Gene: galectin / 33162
• FlyBaseID: FBgn0031213
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_006490.3
• Gene: LGALS8 / 3964
• HGNCID: 6569
• Length: 359
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 101/358 - (28%)
• Similarity: 166/358 - (46%)
• Gaps: 50/358 - (13%)

  Fly   145 KLSEGISFTVTGNLSVNCERFSINLVYNNDSR---DVALHINPRLPQ-NYIVRNTKVQDIWGNEE 205
            :|..|....:.|::..:.:||.::|...:..:   |||.|.|||..: ..||.||.:.:.||.||
Human    26 QLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREE 90

  Fly   206 VSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTL 270
            ::...||  .|.:.|.|.::|.:..:.::|||:|...|.|||....:..|.:.|.| |:   .::
Human    91 ITYDTPF--KREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKV-NI---HSI 149

  Fly   271 VLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIP-HEWCIIS--APNTQSDSSPKRNNSSN 332
            ...:...|..::|:::||   ..|:..:.....|.::| :....||  ||.|....| |.:..::
Human   150 GFSFSSDLQSTQASSLEL---TEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKS-KDSTVNH 210

  Fly   333 DLGLTLPYYGALPPNSLVD---------------GRCLKIEGRVRLLPHSFYINLQQGQDIWPHP 382
            .|..|     .:||.:.|.               ||.:.::|.|.....||.::|..|:.    .
Human   211 TLTCT-----KIPPMNYVSKRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKS----K 266

  Fly   383 VIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVY 447
            .||.|||||.:.       ||.| ||::|..:|.:|||:.....|.||..|.:.|.|....|:|.
Human   267 DIALHLNPRLNI-------KAFV-RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVA 323

  Fly   448 VNRQFMTDFKYKVSP-EVVDTVYIQGDVKLWNV 479
            ||.....::|::... ..:||:.|.||:.|..|
Human   324 VNGVHSLEYKHRFKELSSIDTLEINGDIHLLEV 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025	37/120 (31%)
		Gal-bind_lectin	339..479	CDD:278752	45/155 (29%)
LGALS8	NP_006490.3	Gal-bind_lectin	18..151	CDD:278752	39/130 (30%)
		Gal-bind_lectin	236..356	CDD:214904	42/131 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8848
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4712
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm8457
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4988
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	9.000