DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galectin and LGALS3

DIOPT Version :9

Sequence 1:	NP_608487.1	Gene:	galectin / 33162	FlyBaseID:	FBgn0031213	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001344607.1	Gene:	LGALS3 / 3958	HGNCID:	6563	Length:	264	Species:	Homo sapiens

Alignment Length:	123	Identity:	42/123 - (34%)
Similarity:	61/123 - (49%)	Gaps:	9/123 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 TVTGNLSVNCERFSINLVYNNDSRDVALHINPRLPQN---YIVRNTKVQDIWGNEEVSSALPFLL 214
            |:.|.:..|..|.:::....|   |||.|.|||..:|   .||.|||:.:.||.||..|..||
Human   147 TILGTVKPNANRIALDFQRGN---DVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPF-- 206

  Fly   215 SRGEEFSIQVLVTEACYMISVNGQHFAAYTHRI-PYRDVRILEVKGDVSNVEMKRTLV 271
            ..|:.|.|||||....:.::||..|...|.||: ...::..|.:.||:.......|::
Human   207 ESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025	41/112 (37%)
galectin	NP_608487.1	Gal-bind_lectin	339..479	CDD:278752
LGALS3	NP_001344607.1	DNA_pol3_gamma3	<23..127	CDD:331207
LGALS3	NP_001344607.1	GLECT	131..258	CDD:238025	41/115 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8601
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.919607	Normalized mean entropy	S5429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.770