DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galectin and lgals9l1

DIOPT Version :9

Sequence 1:	NP_608487.1	Gene:	galectin / 33162	FlyBaseID:	FBgn0031213	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_956366.1	Gene:	lgals9l1 / 337597	ZFINID:	ZDB-GENE-030131-9543	Length:	310	Species:	Danio rerio

Alignment Length:	373	Identity:	107/373 - (28%)
Similarity:	157/373 - (42%)	Gaps:	86/373 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 SFYEYADAVPKYFNDQI-------GKLSEGISFTVTGNLSVNCERFSINLVYNNDSR-DVALHIN 183
            :||:.    |.|:|.:|       |.|.:|.|..::|.:.....||.:||...:.|. :||||.|
Zfish     2 AFYQQ----PPYYNPRIPFSGPIQGGLQDGKSIIISGRVLPGANRFHVNLQCGSHSEANVALHFN 62

  Fly   184 PRLPQ-NYIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRI 247
            ||... :|:|.|:.:...||:||.....||  ::|:.|::|:||.:..|.||.||:||..|.|||
Zfish    63 PRYEDTDYVVNNSYLNRTWGSEERKYESPF--AQGQTFTLQILVAQDKYKISTNGRHFMDYKHRI 125

  Fly   248 PYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWC 312
            |:..|..:.|:|.|                    |.|::......|.....|.......:| ..|
Zfish   126 PFTQVDTVAVEGMV--------------------EVNSVAFQNPAGFIPPQAGYAPQYAVP-PGC 169

  Fly   313 ----IISAPNTQSDSSPKRNNSSNDLGLTLPY----YGALPPNSLVDGRCLKIEGRVRLLPHSFY 369
                ..||||                 .|:|:    .|.|.|     |:.:.|.|.|.....|..
Zfish   170 GFPAFPSAPN-----------------YTIPHKTVMNGGLHP-----GKNIVINGVVNPNAKSII 212

  Fly   370 INL--QQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRS 432
            .||  :.|        ||||.||||.        :.||.||......|..|||.. ...|..|:.
Zfish   213 FNLCYRSG--------IAFHYNPRFD--------ENVVVRNTNQMEKWGAEERFG-GLPFHKGQP 260

  Fly   433 FCLAIVCTKTSFEVYVNRQFMTDFKYKVSP-EVVDTVYIQGDVKLWNV 479
            |.:.|.|....:.|:||.:....:|::.:. ..:|.:.|.||::|.:|
Zfish   261 FQVTISCNPQHYNVFVNGKQEHTYKHRYTKLNDIDILEICGDLQLTSV 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025	47/127 (37%)
galectin	NP_608487.1	Gal-bind_lectin	339..479	CDD:278752	42/146 (29%)
lgals9l1	NP_956366.1	Gal-bind_lectin	15..146	CDD:278752	49/152 (32%)
lgals9l1	NP_956366.1	Gal-bind_lectin	189..309	CDD:214904	42/142 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8031
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4720
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm6433
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4988
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.000