DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galectin and LGALSL

DIOPT Version :9

Sequence 1:	NP_608487.1	Gene:	galectin / 33162	FlyBaseID:	FBgn0031213	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_054900.2	Gene:	LGALSL / 29094	HGNCID:	25012	Length:	172	Species:	Homo sapiens

Alignment Length:	190	Identity:	43/190 - (22%)
Similarity:	78/190 - (41%)	Gaps:	38/190 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 IDDG--INEIDASVEETVKIPHEWCIISAPNTQSDSSPKRNNSSNDLGLTLPYYGALPPNSLVDG 352
            :|||  .|.:.:.|:..|..|.                          |.:|:.|.: ...:..|
Human    14 LDDGHLNNSLSSPVQADVYFPR--------------------------LIVPFCGHI-KGGMRPG 51

  Fly   353 RCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQ 417
            :.:.:.|.|.|.|.||.|:|..|....|...:|..|...|:...        :.||:.::|...:
Human    52 KKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQ--------LLRNSCISGERGE 108

  Fly   418 EERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVSP-EVVDTVYIQGDVKL 476
            |:.:.....|.|.:.|.:.|:|....|.|:|:...:.||.:::.. ..:||:.|.||:::
Human   109 EQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQI 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025
galectin	NP_608487.1	Gal-bind_lectin	339..479	CDD:278752	35/139 (25%)
LGALSL	NP_054900.2	Gal-bind_lectin	46..170	CDD:214904	33/131 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8848
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.780