DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galectin and lec-2

DIOPT Version :9

Sequence 1:	NP_608487.1	Gene:	galectin / 33162	FlyBaseID:	FBgn0031213	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001379091.1	Gene:	lec-2 / 174560	WormBaseID:	WBGene00002265	Length:	1245	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	89/357 - (24%)
Similarity:	139/357 - (38%)	Gaps:	86/357 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 YEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNN---DSRDVALHINPRLPQNY 190
            :|.|..|| |.:..:.....|.:..|.|....:..||::||..|.   ...||.||::.|..:..
Worm   970 HESAFPVP-YRSKLVEPFEPGQTLIVKGKTGEDSIRFTVNLHTNTADFSGNDVPLHVSVRFDEGK 1033

  Fly   191 IVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRIL 255
            :|.||..:..||.||..|. |:  .:|::..|::...::.:.|.|:.:....|.||:|...:...
Worm  1034 LVFNTFSKGEWGKEERKSN-PY--KKGDDIDIRIRAHDSKFQIFVDQKEVKEYEHRVPLSSITHF 1095

  Fly   256 EVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQ 320
            .:.|||         ::.|             :|                     |.....|
Worm  1096 TIDGDV---------LVNY-------------IH---------------------WGGKYYP--- 1114

  Fly   321 SDSSPKRNNSSNDLGLTLPYYGALPPNSLVDGRCLKIEGRVRLLPHSFYIN-LQQGQDIWPHPVI 384
                             :||...|....|..|:.|.:.|........|:|| |::..|      |
Worm  1115 -----------------VPYESGLAGEGLAPGKTLTVFGIPEKKAKRFHINLLKKNGD------I 1156

  Fly   385 AFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVN 449
            |.|||.||.:       |.|| ||:.:|.||..||| |....|.....|.|.|.....:|.|.||
Worm  1157 ALHLNARFDE-------KHVV-RNSLINSAWGNEER-EGKMPFEKAVGFDLEIHNEPYAFAVTVN 1212

  Fly   450 RQFMTDFKYKVSPEVVDTVYIQGDVKLWNVTL 481
            .:....:.:::||:.|:.:.|.|||::..:.|
Worm  1213 GERFASYAHRLSPDEVNGLQIGGDVEITGIQL 1244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025	32/121 (26%)
galectin	NP_608487.1	Gal-bind_lectin	339..479	CDD:278752	46/140 (33%)
lec-2	NP_001379091.1	rne	<136..298	CDD:236766
		PRK14949	<235..662	CDD:237863
		rne	<474..771	CDD:236766
		rne	<794..963	CDD:236766
		GLECT	978..1108	CDD:214596	36/175 (21%)
		GLECT	1116..1243	CDD:238025	46/141 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I5463
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		mtm4724
orthoMCL	1	0.900	-	-		OOG6_106881
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820