DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galectin and CLC

DIOPT Version :9

Sequence 1:	NP_608487.1	Gene:	galectin / 33162	FlyBaseID:	FBgn0031213	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001819.2	Gene:	CLC / 1178	HGNCID:	2014	Length:	142	Species:	Homo sapiens

Alignment Length:	156	Identity:	45/156 - (28%)
Similarity:	70/156 - (44%)	Gaps:	26/156 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 LTLPYYGALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAI 400
            |.:||..|.   ||..|..:.|:||    |.:.::|       .|:..:.||..   .|..|..:
Human     4 LPVPYTEAA---SLSTGSTVTIKGR----PLACFLN-------EPYLQVDFHTE---MKEESDIV 51

  Fly   401 GKAVVC--RNAWLN----GAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYK 459
            ....||  |...:|    |||.|:..|: :..|:.|:.|.|:|......::|.||.|....|.::
Human    52 FHFQVCFGRRVVMNSREYGAWKQQVESK-NMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHR 115

  Fly   460 VSPEVVDTVYIQGDVKL--WNVTLEK 483
            :.||.|..|.:..|:.|  :||:..|
Human   116 IKPEAVKMVQVWRDISLTKFNVSYLK 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galectin	NP_608487.1	GLECT	143..262	CDD:238025
galectin	NP_608487.1	Gal-bind_lectin	339..479	CDD:278752	41/147 (28%)
CLC	NP_001819.2	Gal-bind_lectin	5..137	CDD:278752	41/149 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150751
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750