Protein Alignment HSPB2 and Hsp27

DIOPT Version :9

• Sequence 1: NP_001532.1
• Gene: HSPB2 / 3316
• HGNCID: 5247
• Length: 182
• Species: Homo sapiens
• Sequence 2: NP_001287001.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 184
• Identity: 57/184 - (30%)
• Similarity: 82/184 - (44%)
• Gaps: 49/184 - (26%)

Human     8 HAHPATAEYEFANPSR--------LGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGA 64
            |||      :..:|.|        ||.:|:.    |.|     ..||::.:.....:|     |.
  Fly    34 HAH------DLFHPRRLLLPNTLGLGRRRYS----PYE-----RSHGHHNQMSRRASG-----GP 78

Human    65 SELRLSEGK--FQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADV 127
            :.|..:.||  ||..:|||.|.|:|:||:.|||.:.|..:|.:|.|.||.:.|.|.|.|.||...
  Fly    79 NALLPAVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGF 143

Human   128 DPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVE 181
            ||..|.:.:|.||:|.|:|                   |.||..|:.:...||:
  Fly   144 DPNEVVSTVSSDGVLTLKA-------------------PPPPSKEQAKSERIVQ 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB2	NP_001532.1	alpha-crystallin-Hsps_p23-like	67..148	CDD:412199	37/82 (45%)
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	36/95 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.780