DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir21a and GLR3.6

DIOPT Version :9

Sequence 1:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001326369.1	Gene:	GLR3.6 / 824311	AraportID:	AT3G51480	Length:	903	Species:	Arabidopsis thaliana

Alignment Length:	612	Identity:	127/612 - (20%)
Similarity:	208/612 - (33%)	Gaps:	177/612 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 NIVN-----LLVIGE--------------SLM-ADPMRERPYVLYTHKLYADGLGSNTPVVLTSW 256
            |:||     |.|||.              |:| ||.|....:  ...||::.....::..:...|
plant   387 NLVNPAFDVLNVIGTGYTTIGYWFNHSGLSVMPADEMENTSF--SGQKLHSVVWPGHSIKIPRGW 449

  Fly   257 IKGALSRPHINL-FPSKFQF-------------GFAGHRFQISAANQPPFIFRIRTLDSSGMGQL 307
            :.....| |:.: .|::::|             ||....| |:|.|..|:
plant   450 VFSNNGR-HLRIGVPNRYRFEEVVSVKSNGMITGFCVDVF-IAAINLLPY--------------- 497

  Fly   308 RWDGVEFRLLTMISKRLNFSIDITETPTRSN-----TRGVVDTIQEQIIERTVDIGMSGIYITQE 367
               .|.|.|:...:..        :.|:.|.     |.||.|.            |:..|.|..|
plant   498 ---AVPFELVAFGNGH--------DNPSNSELVRLITTGVYDA------------GVGDITIITE 539

  Fly   368 R---------LMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGIFPIV 423
            |         .::|.:.|     .|....|.|.|:    |.:.||...:|:.....:|     ||
plant   540 RTKMADFTQPYVESGLVV-----VAPVRKLGSSAM----AFLRPFTPQMWLIAAASFL-----IV 590

  Fly   424 FTDRLTLSHLMGN------WGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFT 482
            ......|.|...:      ..:|...||:.|.  |..||..     ..|..|..|::: ..|||.
plant   591 GAVIWCLEHKHNDEFRGPPRRQVITTFWFSFS--TLFFSHR-----ETTTSNLGRIVL-IIWLFV 647

  Fly   483 I-IITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLFFRVGTLNNGGWETWFQNSTHIPTSRL---- 542
            : ||.|.||.|:.:.:|:......:..:..|......:|.........:..:..:|..|||
plant   648 VLIINSSYTASLTSILTVHQLSSPIKGIETLQTNHDPIGYPQGSFVRDYLIHELNIHVSRLVPLR 712

  Fly   543 ----YKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEEC-- 601
                |.|....|   .|.|.|.       |.:..:|.:|                 |.||..|
plant   713 SPEEYDKALRDG---PGKGGVA-------AVVDERAYIE-----------------LFLSNRCEF 750

  Fly   602 ------FALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSN 660
                  |.....||.|||.|...:.:.:.||...::|.:.:|.::  |:::::.|   ||.:
plant   751 GIVGQEFTKNGWGFAFPRNSPLAVDVSAAILQLSENGDMQRIRDK--WLLRKACS---LQGA--- 807

  Fly   661 SLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSAASSWSSA 725
               ||  |..:|......|:|::..:...|........::.....:|.:..:.|.:..:|  .||
plant   808 ---EI--EVDRLELKSFWGLFVVCGVACVLALAVYTVLMIRQFGQQCPEEAEGSIRRRSS--PSA 865

  Fly   726 SSGSMLRTNAEQLSHDKRKANRREAAE 752
            ...|.|....|:....|.:::|....|
plant   866 RIHSFLSFVKEKEEDAKARSSRERQLE 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	65/322 (20%)
Ir21a	NP_001097043.1	Lig_chan	407..662	CDD:278489	60/277 (22%)
GLR3.6	NP_001326369.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000