Protein Alignment Ir21a and GLR2

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001318239.1
• Gene: GLR2 / 816231
• AraportID: AT2G17260
• Length: 925
• Species: Arabidopsis thaliana
• Alignment Length: 940
• Identity: 173/940 - (18%)
• Similarity: 300/940 - (31%)
• Gaps: 311/940 - (33%)

  Fly    45 IFGVGMCDGNNEN-EFRQKRRIV---PTFQGNPRPR---------------GELLASKFHVNSYN 90
            |||:....|...| .|:.....|   |:|.|..:.|               |.|...:..|.:..
plant    39 IFGLNTMYGETANIAFKAAEEDVNSDPSFLGGSKLRILMNDAKRSGFLSIMGALQFMETDVVAII 103

  Fly    91 FEQTNSLVGLVNKIAQEY---------LNKCPPVIYYDSFVE--KSDGLILENLFKTIPITFY-H 143
            ..||:.:..:::.:|.|.         |:.....:.:..||:  .||..::..:.:.  ||:| .
plant   104 GPQTSIMAHVLSHLANELTVPMLSFTALDPTLSPLQFPFFVQTAPSDLFLMRAIAEM--ITYYGW 166

  Fly   144 GEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTR---------------------------KI 181
            .::.|.|         :.|.|.::.:..|.|.|..|                           ||
plant   167 SDVVALY---------NDDDNSRNGVTALGDELEERRCKISYKAVLPLDVVITSPVEIIEELIKI 222

  Fly   182 LGPQTESRVVLVS--------------------RSTQWRLRDFLSSELSSN------IVNLLVIG 220
            .|  .||||::|:                    :...|....:|||.|.||      :||.::..
plant   223 RG--MESRVIVVNTFPNTGKMIFKEAERLGMMEKGYVWIATTWLSSVLDSNLPLDTKLVNGVLTL 285

  Fly   221 ESLMADPMRERPYVLYTHKLYADGLGSNTPVVL---------TSWI------------------- 257
            .....|..::|.:.    ..:.:.|.:|..:.|         |.||
plant   286 RLHTPDSRKKRDFA----ARWKNKLSNNKTIGLNVYGLYAYDTVWIIARAVKTLLEAGGNLSFSN 346

  Fly   258 -------KG------ALSR---------------------------------PH---INLFPSK- 272
                   ||      ||||                                 |.   |||...:
plant   347 DAKLGSLKGEALNLSALSRFDQGSQLLDYIVHTKMSGLTGPVQFHPDRSMLQPSYDIINLVDDRV 411

  Fly   273 FQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQ----LRWDGVEF-------------RLLTMI 320
            .|.|:..:...:|..  ||..|..:..:.|...|    :.|.|...             ||...:
plant   412 HQIGYWSNYSGLSIV--PPESFYSKPPNRSSSNQHLNSVTWPGGTSVTPRGWIFRNNGRRLRIGV 474

  Fly   321 SKRLNFS-----------------IDITETPTRSNT-----------RGVVDTIQEQIIERT--- 354
            ..|.:|.                 ||:.|...:..:           .|:.:....:::.:.
plant   475 PDRASFKDFVSRVNGSSNKVQGYCIDVFEAAVKLLSYPVPHEFIFFGDGLTNPNYNELVNKVTTG 539

  Fly   355 VD----IGMSGIYITQERLMDSAMSVGHSPDCAAFITLASKALPKYR------AIMGPFQWPVWV 409
            ||    :|...|...:.|::|.......|    ..:.:|    |..|      |.:.||..|:|.
plant   540 VDFDAVVGDIAIVTKRTRIVDFTQPYIES----GLVVVA----PVTRLNENPWAFLRPFTLPMWA 596

  Fly   410 ALICVYLGGIFPIVFTDRLTLSHLMGN------WGEVENMFWYVFG-MFTNAFSFTGKYSWSNTR 467
            .     ....|.||......|.|.:.:      ..::..:.|:.|. ||         :|...|.
plant   597 V-----TASFFVIVGAAIWILEHRINDEFRGPPRRQIITILWFTFSTMF---------FSHRETT 647

  Fly   468 KNSTRLLIGAYWLFTI-IITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLFFRVGTLNNGGWETWF 531
            .::...::...|||.: ||||.||.|:.:.:|:......:..|..|:....|:|.......|.:.
plant   648 VSTLGRMVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIKGVDTLISSTGRIGFQVGSFAENYM 712

  Fly   532 QNSTHIPTSRLYKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALH 596
            .:..:|.:|||..    :.|.:| ..|..|:        |:.|.:  :.:..:.|        |.
plant   713 TDELNIASSRLVP----LASPEE-YANALQN--------GTVAAI--VDERPYID--------LF 754

  Fly   597 LSEEC--------FALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRL 653
            ||:.|        |.....||.|||:|...:.:.:.||...::|.:.||::.  |:.:.:.|..
plant   755 LSDYCKFAIRGQEFTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQKIHDR--WLSKSNCSSP- 816

  Fly   654 LQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSA 718
             ..|.|.       :..||......||||::.:...:.......:|:........:::......:
plant   817 -HGSQSG-------DSEQLNVHSFWGMFLVVGIACLVALFIHFFKIIRDFCKDTPEVVVEEAIPS 873

  Fly   719 ASSWSSASSGSMLRTNAEQLSHDKRKANRR 748
            ..|.......:.|....|:....||:..|:
plant   874 PKSSRLTKLQTFLAFVDEKEEETKRRLKRK 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	23/156 (15%)
		Lig_chan	405..662	CDD:459656	60/272 (22%)
GLR2	NP_001318239.1	PBP1_GABAb_receptor_plant	35..427	CDD:380645	72/406 (18%)
		GluR_Plant	468..808	CDD:270404	77/386 (20%)
		Lig_chan	591..842	CDD:459656	66/298 (22%)