Protein Alignment Ir21a and grik1a

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_009303592.1
• Gene: grik1a / 798001
• ZFINID: ZDB-GENE-030131-6502
• Length: 919
• Species: Danio rerio
• Alignment Length: 619
• Identity: 127/619 - (20%)
• Similarity: 217/619 - (35%)
• Gaps: 168/619 - (27%)

  Fly   183 GPQTESRVVLVSRSTQW---------RLRDFLSSELSSNIVNLLVIGESLMADPMRERPYVLYT- 237
            ||    |.:.:.:..||         ...|.|..|.:.::::|...|.:........||..|:|
Zfish   359 GP----RFMNLFKEAQWDGLTGRIVLNKTDGLRKEFNLDLISLKEDGTAKRVADGASRPNKLWTK 419

  Fly   238 -----------------HKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQIS 285
                             :|...|.|.:.|.:|.|     .|..|::
Zfish   420 IGVWNSYTGLNLTEIKDNKNITDSLANRTLIVTT-----ILENPYV------------------- 460

  Fly   286 AANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMISKRLNFSIDITETPT----RSNTRGVVDTI 346
                     ..:..|....|..|::|....||..:|..|.|:.::.....    ..|.:|..:.:
Zfish   461 ---------MYKKSDKVLYGNDRFEGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDKGEWNGM 516

  Fly   347 QEQIIERTVDIGMSGIYIT--QERLMDSAMSVGHSPDCAAFITLASKAL--------PKYRAIMG 401
            ..::|:...|:.::.:.||  :|:::|.:         ..|:||....|        |...:.:.
Zfish   517 VRELIDHIADLAVAPLTITYVREKVIDFS---------KPFMTLGISILYRKPNGTNPGVFSFLN 572

  Fly   402 PFQWPVWVALICVYLGGIFPIVFTDRLT-----LSHLMGNWGE-VENMFWYVFGMFTNAFSFTGK 460
            |....:|:.::...||....:....|.|     ..|......| |||.|..:..::....:...:
Zfish   573 PLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPSSEVVENNFTLLNSLWFGVAALMRQ 637

  Fly   461 YSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNN 524
            .|....:..|||:|.|.:|.||:||.|.||.::.||:|:......:||..||. ......|.:.:
Zfish   638 GSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTRIEYGAVRD 702

  Fly   525 GGWETWFQNSTHIPTSRLYKKM-EFVGS------VDEGIGNVTQSFFWNYAFLGSKAQLEYLVQS 582
            |...|:|:.| .|.|   |:|| .|:.|      |......:|:....:||.|.....:||:.|.
Zfish   703 GSTMTFFKKS-KIST---YEKMWAFMSSRKNTALVKNSKDGITRVLTTDYALLMESTSIEYITQR 763

  Fly   583 NFSDENISRRSALHLSEECFALFQIGFLF---------PRESVYKIKIDSMILLAQQSGLIAKIN 638
            |.:                  |.|:|.|.         |..|.|:.|:...||..|:.|.: .:.
Zfish   764 NCN------------------LTQVGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKL-HMM 809

  Fly   639 NEVSWVMQRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVG-- 701
            .|..|             ..:....|..:|...|...:..|:|:::|.|..|.....:.|.:.
Zfish   810 KEKWW-------------RGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKS 861

  Fly   702 -------------------GITNKCRQII-KRSR 715
                               ||:.:|.:.: ||.|
Zfish   862 HKNSDIEECVSFSAVMEDLGISLRCHKALRKRGR 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	75/321 (23%)
		Lig_chan	407..662	CDD:278489	67/277 (24%)
grik1a	XP_009303592.1	Periplasmic_Binding_Protein_Type_1	37..432	CDD:299141	14/76 (18%)
		ANF_receptor	57..398	CDD:279440	8/42 (19%)
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:304360	95/446 (21%)
		Lig_chan	577..846	CDD:278489	73/304 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810