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Protein Alignment Ir21a and Gria3

DIOPT Version :9

Sequence 1:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	711	Identity:	132/711 - (18%)
Similarity:	246/711 - (34%)	Gaps:	227/711 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 SDGLILENLFKTIPITFYHGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESR 189
            |.|:.:|...|.:.:....|.|..|...:...:|  ||             :...|:.|.:
Mouse   343 SQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYT--ID-------------VYEMKVSGSR---- 388

  Fly   190 VVLVSRSTQW----RLRDFLSSEL---SSNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGS 247
                 ::..|    |...|...::   ||:..|..::..:::     |.|||:|
Mouse   389 -----KAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTIL-----ESPYVMY----------- 432

  Fly   248 NTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGV 312
                          .:.|..|                                   .|..|::|.
Mouse   433 --------------KKNHEQL-----------------------------------EGNERYEGY 448

  Fly   313 EFRLLTMISK--RLNFSIDI-------TETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYIT--Q 366
            ...|...|:|  |:.:.:.|       ...|......|:|.    :::....||.::.:.||  :
Mouse   449 CVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVG----ELVYGRADIAVAPLTITLVR 509

  Fly   367 ERLMDSA---MSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGIFPIVFTDRL 428
            |.::|.:   ||:|.|    ..|....|:.|...:.:.|..:.:|:.::..|: |:..::|
Mouse   510 EEVIDFSKPFMSLGIS----IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI-GVSVVLF---- 565

  Fly   429 TLSHLMGNWGEVENMFWYV-------------------FGMFTNAFSFTGKYSWS----NTRKNS 470
                |:..:...|   |::                   ||:|.:.:...|.:...    :.|..|
Mouse   566 ----LVSRFSPYE---WHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 623

  Fly   471 TRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNNGGWETWFQNS 534
            .|::.|.:|.||:||.|.||.::.||:|:......::|..||. ......|||::|..:.:|:.|
Mouse   624 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRS 688

  Fly   535 THIPTSRLYKKME------FVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDE-----N 588
            ......:::..|:      |..:..:|:..|.:| ...:|||......||:.|....|.     |
Mouse   689 KIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKS-KGKFAFLLESTMNEYIEQRKPCDTMKVGGN 752

  Fly   589 ISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRL 653
            :..:.             .|...|:.|..:..::..:|...:.|::.|:.|:  |...:...|
Mouse   753 LDSKG-------------YGVATPKGSALRTPVNLAVLKLSEQGILDKLKNK--WWYDKGECG-- 800

  Fly   654 LQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSA 718
              |..|.|.    .:...|:.::..|:|.::..|  ||...:|:            :|:...||.
Mouse   801 --AKDSGSK----DKTSALSLSNVAGVFYILVGG--LGLAMMVA------------LIEFCYKSR 845

  Fly   719 ASSWSSASSGSMLRTNAEQLSHDKRKANRREAAEVAQKMSFGMRELNLTRATLREIYGSYG 779
            |.|              :::...|...|.:.|.....:          ..||.||.|..||
Mouse   846 AES--------------KRMKLTKNTQNFKPAPATNTQ----------NYATYREGYNVYG 882

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.