Protein Alignment Ir21a and grin2da

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_073787594.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1918
• Species: Danio rerio
• Alignment Length: 609
• Identity: 119/609 - (19%)
• Similarity: 213/609 - (34%)
• Gaps: 135/609 - (22%)

  Fly   143 HGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFLSS 207
            ||.:....|....|.||... ||      :.|...|:::.|                |:|.|.:.
Zfish   349 HGAMALRREYGGARGTSFAG-NC------MMDGNQTQRVPG----------------RIRFFSNI 390

  Fly   208 ELSSNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSK 272
            .||..  :.....:..:|:|:.:  .:.||.....:.:|        .|..|.|..    .:|..
Zfish   391 TLSGR--DYSFNNDGYLANPLLD--VISYTAGRGWEEVG--------WWENGVLRL----RYPPW 439

  Fly   273 FQFG-FA-----GHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRL--------------- 316
            .::| |.     ....::....:.||:. :...| .|.|....|.|..||
Zfish   440 SRYGPFLKPLDDSQHLRVVTLEERPFVI-VEPAD-PGTGSCIRDSVPCRLPLNNRSSMVVEGIQS 502

  Fly   317 ------------LTMISKRLNFSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQ 366
                        |..::|.:.|:.|   :|......|..|..:.:..:::.:..|:.:..:.|.:
Zfish   503 MKHCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNIDGQWNGMVGEVVSKRADMAIGSLTINE 567

  Fly   367 ERLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVAL---------ICVYLGGIF-P 421
            ||......||.......:.:...|.......|.:.|:...|||.:         :.|::...| |
Zfish   568 ERSEVVEFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFEFFSP 632

  Fly   422 IVFTDRLTLSHLMGNWGE---VENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTI 483
            :.:...|......|  |.   :....|.::     |..|.......|.|..::::::..:..|.:
Zfish   633 VGYNRSLQSGKTAG--GSKFTIGKSIWLLW-----ALVFNNSVPVENPRGTTSKIMVLVWAFFAV 690

  Fly   484 IITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLF---------FRVGTLNNGGWETWFQN-STHIP 538
            |..:.||.::.||:....:.|||..:.|  ..|         .|.||:.||..|   :| .::.|
Zfish   691 IFLASYTANLAAFMIQEEYIDTVSGLSD--KKFQHPTEQYPPLRFGTVPNGSTE---ENIRSNYP 750

  Fly   539 TSRLYKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECFA 603
            ....|........|::.|.|:.....  .||:...|.|.|:.:   .||.....:.  .|.:.||
Zfish   751 NMHQYMVRNNQRGVEDAIENLKTGKL--DAFIYDAAVLNYMAR---KDEGCKVMTI--GSGKVFA 808

  Fly   604 LFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQE 668
            ....|....:.|.:|..:|  :.|.|..|     ::|:..:.:...||     ...|...|::..
Zfish   809 TTGYGVALHKNSRWKRPLD--LALLQLVG-----DDEIDMLERLWLSG-----ICHNDKIEVMSS 861

  Fly   669 ERQLTTADTEGMF--LLMALGYFL 690
              :|...:..|:|  ||:|:|..|
Zfish   862 --KLDIDNMAGVFYMLLVAMGLSL 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	23/134 (17%)
		Lig_chan	405..662	CDD:459656	58/279 (21%)
grin2da	XP_073787594.1	None