Protein Alignment Ir21a and grin2da

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 607
• Identity: 119/607 - (19%)
• Similarity: 213/607 - (35%)
• Gaps: 133/607 - (21%)

  Fly   143 HGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFLSS 207
            ||.:....|....|.||... ||      :.|...|:::.|                |:|.|.:.
Zfish   349 HGAMALRREYGGARGTSFAG-NC------MMDGNQTQRVPG----------------RIRFFSNI 390

  Fly   208 ELSSNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSK 272
            .||..  :.....:..:|:|:.:  .:.||.....:.:|        .|..|.|..    .:|..
Zfish   391 TLSGR--DYSFNNDGYLANPLLD--VISYTAGRGWEEVG--------WWENGVLRL----RYPPW 439

  Fly   273 FQFG-FA-----GHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRL--------------- 316
            .::| |.     ....::....:.||:. :...| .|.|....|.|..||
Zfish   440 SRYGPFLKPLDDSQHLRVVTLEERPFVI-VEPAD-PGTGSCIRDSVPCRLPLNNSMVVEGIQSMK 502

  Fly   317 ----------LTMISKRLNFSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQER 368
                      |..::|.:.|:.|   :|......|..|..:.:..:::.:..|:.:..:.|.:||
Zfish   503 HCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNIDGQWNGMVGEVVSKRADMAIGSLTINEER 567

  Fly   369 LMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVAL---------ICVYLGGIF-PIV 423
            ......||.......:.:...|.......|.:.|:...|||.:         :.|::...| |:.
Zfish   568 SEVVEFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFEFFSPVG 632

  Fly   424 FTDRLTLSHLMGNWGE---VENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIII 485
            :...|......|  |.   :....|.::     |..|.......|.|..::::::..:..|.:|.
Zfish   633 YNRSLQSGKTAG--GSKFTIGKSIWLLW-----ALVFNNSVPVENPRGTTSKIMVLVWAFFAVIF 690

  Fly   486 TSCYTGSIIAFVTLPAFPDTVDSVLDLLGLF---------FRVGTLNNGGWETWFQN-STHIPTS 540
            .:.||.::.||:....:.|||..:.|  ..|         .|.||:.||..|   :| .::.|..
Zfish   691 LASYTANLAAFMIQEEYIDTVSGLSD--KKFQHPTEQYPPLRFGTVPNGSTE---ENIRSNYPNM 750

  Fly   541 RLYKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECFALF 605
            ..|........|::.|.|:.....  .||:...|.|.|:.:   .||.....:.  .|.:.||..
Zfish   751 HQYMVRNNQRGVEDAIENLKTGKL--DAFIYDAAVLNYMAR---KDEGCKVMTI--GSGKVFATT 808

  Fly   606 QIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQEER 670
            ..|....:.|.:|..:|  :.|.|..|     ::|:..:.:...||     ...|...|::..
Zfish   809 GYGVALHKNSRWKRPLD--LALLQLVG-----DDEIDMLERLWLSG-----ICHNDKIEVMSS-- 859

  Fly   671 QLTTADTEGMF--LLMALGYFL 690
            :|...:..|:|  ||:|:|..|
Zfish   860 KLDIDNMAGVFYMLLVAMGLSL 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	67/344 (19%)
		Lig_chan	407..662	CDD:278489	58/277 (21%)
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	25/130 (19%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	82/431 (19%)
		HisJ	<507..>590	CDD:223904	13/82 (16%)
		Lig_chan	605..877	CDD:278489	64/304 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900