Protein Alignment Ir21a and Ir93a

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Alignment Length: 779
• Identity: 156/779 - (20%)
• Similarity: 288/779 - (36%)
• Gaps: 175/779 - (22%)

  Fly     5 WVALVLFTAQAFSIEGDRSASYQEKCISRRLINH--------YQLNKEIFG----------VGMC 51
            |...|:|..|...   :.:|...:..:...:.||        |::|..:.|          :...
  Fly   163 WKTAVVFVDQTIL---EENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVALRQALSQF 224

  Fly    52 DGNNENEFRQKRRIVPTFQGNPRPRGELLASKFHVNSYNFEQTNSLVGLVNKIAQEY-------- 108
            ......|.||:..::..|..:.....|.| :.|||.:      ..::.:::.:|:::
  Fly   225 APKKHEEMRQQFLVISAFHEDIIEIAETL-NMFHVGN------QWMIFVLDMVARDFDAGTVTIN 282

  Fly   109 ----------LNKCPPVIYYDSF--VEKSDGLILENLFKTIPI--TFYHGEINADYEAKNKRFTS 159
                      ||:..|.. .||.  ......|.|.|....|.:  ...:||| :|.|.:..|||.
  Fly   283 LDEGANIAFALNETDPNC-QDSLNCTISEISLALVNAISKITVEEESIYGEI-SDEEWEAIRFTK 345

  Fly   160 HIDCNCKSYIL-FLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFLSSELSSNIVNLLVIGESL 223
            .   ..::.|| ::.:.|.|.           ...|...:||:...::...|..       ....
  Fly   346 Q---EKQAEILEYMKEFLKTN-----------AKCSSCARWRVETAITWGKSQE-------NRKF 389

  Fly   224 MADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQ----- 283
            .:.|.|:..    ........:|..|||:  .::...|:.|||.            |.|:
  Fly   390 RSTPQRDAK----NRNFEFINIGYWTPVL--GFVCQELAFPHIE------------HHFRNITMD 436

  Fly   284 ISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMISKRLNFSIDI------TETPTRSNTRG- 341
            |...:.||  ::|.|.:|:|: .:...|:...::..:|:.||||..:      .|..:.|.:.|
  Fly   437 ILTVHNPP--WQILTKNSNGV-IVEHKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGG 498

  Fly   342 -----VVDTIQEQIIERTVDIGMSGIYITQERLMDSAMSVGHSPDCA-------------AFITL 388
                 :|.::..:|..|.|::.....:     .:.:..:....||..             :|||.
  Fly   499 NESDELVGSMTFRIPYRVVEMVQGNQF-----FIAAVAATVEDPDQKPFNYTQPISVQKYSFITR 558

  Fly   389 ASKALPKYRAIMGPFQWPVWVALICVYLGGIFPIVFTDRLTLSHLMGNWG--EVENMFWYVFGMF 451
            ....:.:......||....|..|:.:.|.....:...:||.....|...|  .|::.|||:||..
  Fly   559 KPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLKEMRIVGLSTVKSCFWYIFGAL 623

  Fly   452 TNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSV------L 510
            ...   .|.|.   ...:|.||::|.:|:..|::.:.|.|:::||:|.|.|...||.:      .
  Fly   624 LQQ---GGMYL---PTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHK 682

  Fly   511 DLLGLFFRVGTLNNGGWETWFQNSTHIPTSRLYKKMEFVGSV-DEGIGNVTQ----SFFWNYAFL 570
            |::....|.||.    :|.:.|::|........::.:..||. :|.|..|.:    :..|
  Fly   683 DIVQYGLRNGTF----FERYVQSTTREDFKHYLERAKIYGSAQEEDIEAVKRGERINIDW----- 738

  Fly   571 GSKAQLEYLVQSNFSDENISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIA 635
              :..|:.:||.:|..|   :.....|..|.|...||..:.|.:|.|...::..|....:.|.|.
  Fly   739 --RINLQLIVQRHFERE---KECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIE 798

  Fly   636 KINNEVSW-VMQRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSE 698
            :      | .|...|:|:   .:..::.|::  ...::...|.:|.||::.||:.|....:..|
  Fly   799 R------WHQMNLPSAGK---CNGKSAQRQV--TNHKVNMDDMQGCFLVLLLGFTLALLIVCGE 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	24/129 (19%)
		Lig_chan	405..662	CDD:459656	63/270 (23%)
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	62/285 (22%)
		Lig_chan	574..836	CDD:459656	67/292 (23%)