Protein Alignment Ir21a and Ir75d

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Alignment Length: 697
• Identity: 123/697 - (17%)
• Similarity: 230/697 - (32%)
• Gaps: 242/697 - (34%)

  Fly    34 RLINHYQLNKEIFGVGMCDGNNENEFRQKRRI--VPTFQGNPRPRGELLASKFHVNSYNFEQTNS 96
            :|..|:.||.....|     :.|:..|..:.:  :...:..|.|:      .||.|:....:|:.
  Fly    78 KLWQHFNLNNFYVQV-----STESSLRDLQHVDALDEHKDAPPPK------SFHANNSTHWETSF 131

  Fly    97 LVGLVNKIAQEYLNKCPPVIYYDSFVEKSDGLILE-------NLFKTIPITFYHGEINADYEAKN 154
            |:               |.:.|     |...|:||       ||.:.            ...:::
  Fly   132 LL---------------PALPY-----KMGILLLEFSSECALNLLRW------------SAASEH 164

  Fly   155 KRFTSHIDCNCKSYILFLSDP-----LMTRKI-LGPQTESRVVLVSRSTQWRLRDFLSSELSSNI 213
            ..||::     :.::|...||     |...:| :.|.:|.||:....          ....|.::
  Fly   165 NYFTTN-----RFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYEN----------VGNFSCSL 214

  Fly   214 VNLLVIG------ESLMADPMRERPYVLY---------THKLYADGLGSNTPVVLTSWIKGALSR 263
            ::|..:.      .:|:...:|...:|::         |::...:|:..|:.:|:.
  Fly   215 IDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIA--------- 270

  Fly   264 PHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMISKRLNFSI 328
                 ||..|.        .|...:       :|.:|:...       |..||:..::.|||.|.
  Fly   271 -----FPDLFT--------NIEDLS-------LRHIDTISK-------VNHRLMLELANRLNMSY 308

  Fly   329 DITETPTRS--NTRGVVDTIQEQIIERTVDIGMSGIYITQERLMDSAMSVGHSPDCAAFITLASK 391
            :..:|....  ...|..|.:..:.....:|:....|::..:|                 |.|...
  Fly   309 NTYQTVNYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDR-----------------IALVDF 356

  Fly   392 ALPKYRAIMG-----------------PFQWPVWVALICVYLGGIFPIVFTDRLTLS---HLMGN 436
            ....||...|                 ||:..|||:::.:.:  |..:|....|..|   |.|..
  Fly   357 VAETYRVRAGIMFRQPPLSAVANIFAMPFENDVWVSILMLLI--ITTVVLVLELFFSPHNHDMSY 419

  Fly   437 -------WGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSII 494
                   ||.:....:||                 ..|..|.|:::...::..:.:.:.::.:|:
  Fly   420 MDTLNFVWGAMCQQGFYV-----------------EVRNRSARIIVFTTFVAALFLFTSFSANIV 467

  Fly   495 AFVTLPAFPDTVDSVLDLLGLFFRVGTLNNGGWETWFQNSTHIPTSRLYKKMEFVGSVDEGIGNV 559
            |.:..|:  |.:.|:.||......:|..:....:.:|..||...|..||.|.  :.|..|.|
  Fly   468 ALLQSPS--DAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKK--IASKGENI--- 525

  Fly   560 TQSFFWNYAFLGSKA--------QLE-----YLVQSNFSDENISRRSALHLSEECFAL----FQI 607
                 :....||.:.        |:|     .:|...||:           .|:|..:    ||:
  Fly   526 -----YMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSE-----------PEKCGLMELEPFQL 574

  Fly   608 GFL-------FPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQR 647
            ..|       ||    ||..|...:...::..|:.:  .|..|:.|:
  Fly   575 PMLAIPTRKNFP----YKELIRRQLRWQREVSLVNR--EERKWIPQK 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	17/106 (16%)
		Lig_chan	405..662	CDD:459656	55/277 (20%)
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	15/89 (17%)
		Lig_chan	386..643	CDD:459656	55/278 (20%)